Andorfer, Kornelia E. C. and Seebauer, Caroline T. and Dienemann, Carolin and Marcrum, Steven C. and Fischer, Rene and Bohr, Christopher and Kuehnel, Thomas S. (2022) HHT-Related Epistaxis and Pregnancy-A Retrospective Survey and Recommendations for Management from an Otorhinolaryngology Perspective. JOURNAL OF CLINICAL MEDICINE, 11 (8): 2178. ISSN , 2077-0383
Full text not available from this repository. (Request a copy)Abstract
Appropriate management of hereditary hemorrhagic telangiectasia (HHT) is of particular importance in females, as HHT-mediated modifications of the vascular bed and circulation are known to increase the risk of complications during pregnancy and delivery. This study was undertaken to evaluate female HHT patients' awareness of and experience with HHT during pregnancy and delivery, with a focus on epistaxis. In this retrospective study, 46 females (median age: 60 years) with confirmed HHT completed a 17-item questionnaire assessing knowledge of HHT and its pregnancy-associated complications, the severity of epistaxis during past pregnancies and deliveries, and the desire for better education and counselling regarding HHT and pregnancy. Results revealed that 85% of participants were unaware of their disease status prior to the completion of all pregnancies. Further, 91% reported no knowledge of increased pregnancy-related risk due to HHT. In regard to epistaxis, 61% of respondents reported experiencing nosebleeds during pregnancy. Finally, approximately a third of respondents suggested that receiving counseling on the risks of HHT in pregnancy could have been helpful. Findings suggest that awareness of HHT and its potential for increasing pregnancy-related risk is poor. Best practices in HHT management should be followed to minimize negative effects of the disorder.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEREDITARY HEMORRHAGIC TELANGIECTASIA; TRANEXAMIC ACID; WOMEN; hereditary hemorrhagic telangiectasia; Morbus Osler; Rendu-Osler-Weber syndrome; Osler Calendar; orphan disease; pregnancy; epistaxis; arteriovenous malformations; laser therapy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Jan 2024 07:55 |
| Last Modified: | 09 Jan 2024 07:55 |
| URI: | https://pred.uni-regensburg.de/id/eprint/57077 |
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