Gakis, G. and Stenzl, A. and Horn, T. and Gschwend, J. E. and Otto, W. and Burger, M. (2015) Non-muscle-invasive high-grade bladder cancer. UROLOGE, 54 (4). pp. 491-498. ISSN 0340-2592, 1433-0563
Full text not available from this repository. (Request a copy)Abstract
Non-muscle-invasive bladder cancer with a low-grade differentiation represents a special challenge. Although urine cytology is still the most reliable and effective urine-based marker and there are no substantial novel aspects in this field, photodynamic diagnostics have the most important value in transurethral resection of the bladder (TURB) of high-grade T1 tumors and new techniques, such as hybrid knife TURB are coming up. The histopathological assessment of T1 tumors can be supplemented by a description of the exact penetration depth, so-called substaging and the invasion pattern. Intravesicle therapy with Bacillus Calmette-GuSrin (BCG) represents the gold standard and a pillar of bladder-preserving therapy and should be planned as maintenance therapy for at least 1 year. With the right risk constellation cystectomy is a safe and proven concept for high-grade bladder cancer, even without proof of muscle invasion.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BACILLUS-CALMETTE-GUERIN; TRANSITIONAL-CELL-CARCINOMA; RESTAGING TRANSURETHRAL RESECTION; GROUP RANDOMIZED PHASE-3; URINE-BASED MARKERS; UROTHELIAL CARCINOMA; RADICAL CYSTECTOMY; PHOTODYNAMIC DIAGNOSIS; PROGNOSTIC VALUE; FOLLOW-UP; Diagnostics, photodynamic; Invasion pattern; Therapy, intravesicle; Therapy, bladder preserving; Cystectomy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Jul 2019 14:05 |
| Last Modified: | 22 Jul 2019 14:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/5717 |
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