Postoperative Delirium after Reconstructive Surgery in the Head and Neck Region

Taxis, Juergen and Spoerl, Steffen and Broszio, Andreas and Eichberger, Jonas and Grau, Elisabeth and Schuderer, Johannes and Ludwig, Nils and Gottsauner, Maximilian and Spanier, Gerrit and Bundscherer, Annika and Reichert, Torsten E. and Ettl, Tobias (2022) Postoperative Delirium after Reconstructive Surgery in the Head and Neck Region. JOURNAL OF CLINICAL MEDICINE, 11 (22): 6630. ISSN , 2077-0383

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Abstract

Postoperative delirium (POD) is an acute and serious complication following extended surgery. The aim of this study was to identify possible risk factors and scores associated with POD in patients undergoing reconstructive head and neck surgery. A collective of 225 patients was retrospectively evaluated after receiving reconstructive surgery in the head and neck region, between 2013 to 2018. The incidence of POD was examined with regards to distinct patient-specific clinical as well as perioperative parameters. Uni- and multivariate statistics were performed for data analysis. POD occurred in 49 patients (21.8%) and was strongly associated with an increased age-adjusted Charlson Comorbidity Index (ACCI) and a prolonged stay in the ICU (p = 0.009 and p = 0.000, respectively). Analogous, binary logistic regression analysis revealed time in the ICU (p < 0.001), an increased ACCI (p = 0.022) and a Nutritional Risk Screening (NRS) score not equal 0 (p = 0.005) as significant predictors for a diagnosis of POD. In contrast, the extent of reconstructive surgery in terms of parameters such as type of transplant or duration of surgery did not correlate with the occurrence of POD. The extension of reconstructive interventions in the head and neck region is not decisive for the development of postoperative delirium, whereas patient-specific parameters such as age and comorbidities, as well as nutritional parameters, represent predictors of POD occurrence.

Item Type: Article
Uncontrolled Keywords: CHARLSON COMORBIDITY INDEX; RISK-FACTORS; MAJOR HEAD; MOTOR SUBTYPES; CANCER; SYMPTOMS; delirium; head neck squamous cell carcinoma; HNSCC; free flap; Charlson Comorbidity Index
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Feb 2024 07:10
Last Modified: 14 Feb 2024 07:10
URI: https://pred.uni-regensburg.de/id/eprint/57240

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