Contribution of Symptomatic, Herbal Treatment Options to Antibiotic Stewardship and Microbiotic Health

Nausch, Bernhard and Bittner, Claudia B. and Hoeller, Martina and Abramov-Sommariva, Dimitri and Hiergeist, Andreas and Gessner, Andre (2022) Contribution of Symptomatic, Herbal Treatment Options to Antibiotic Stewardship and Microbiotic Health. ANTIBIOTICS-BASEL, 11 (10): 1331. ISSN 2079-6382,

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Abstract

Epithelial surfaces in humans are home to symbiotic microbes (i.e., microbiota) that influence the defensive function against pathogens, depending on the health of the microbiota. Healthy microbiota contribute to the well-being of their host, in general (e.g., via the gut-brain axis), and their respective anatomical site, in particular (e.g., oral, urogenital, skin, or respiratory microbiota). Despite efforts towards a more responsible use of antibiotics, they are often prescribed for uncomplicated, self-limiting infections and can have a substantial negative impact on the gut microbiota. Treatment alternatives, such as non-steroidal anti-inflammatory drugs, may also influence the microbiota; thus, they can have lasting adverse effects. Herbal drugs offer a generally safe treatment option for uncomplicated infections of the urinary or respiratory tract. Additionally, their microbiota preserving properties allow for a more appropriate therapy of uncomplicated infections, without contributing to an increase in antibiotic resistance or disturbing the gut microbiota. Here, herbal treatments may be a more appropriate therapy, with a generally favorable safety profile.

Item Type: Article
Uncontrolled Keywords: herbal drugs; gut microbiota; antibiotic stewardship; uncomplicated infection; NSAID; homeostasis
Subjects: 500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Petra Gürster
Date Deposited: 01 Aug 2024 10:07
Last Modified: 01 Aug 2024 10:07
URI: https://pred.uni-regensburg.de/id/eprint/57333

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