Konzok, Julian and Henze, Gina-Isabelle and Kreuzpointner, Ludwig and Peter, Hannah L. and Giglberger, Marina and Bartl, Christoph and Massau, Claudia and Kargel, Christian and Weidacker, Kathrin and Schiffer, Boris and Eisenbarth, Hedwig and Wust, Stefan and Kudielka, Brigitte M. (2022) Dissociation of behavioral and neural responses to provocation during reactive aggression in healthy adults with high versus low externalization. COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE, 22 (5). pp. 1130-1144. ISSN 1530-7026, 1531-135X
Full text not available from this repository. (Request a copy)Abstract
The externalizing spectrum describes a range of heterogeneous personality traits and behavioral patterns, primarily characterized by antisocial behavior, disinhibition, and substance (mis)use. In psychopathology, abnormalities in neural threat, reward responses and the impulse-control system may be responsible for these externalizing symptoms. Within the non-clinical range, mechanisms remain still unclear. In this fMRI-study, 61 healthy participants (31 men) from the higher versus lower range of the non-clinical variation in externalization (31 participants with high externalization) as assessed by the subscales disinhibition and meanness of the Triarchic-Psychopathy-Measure (TriPM) performed a monetary modified Taylor-Aggression-Paradigm (mTAP). This paradigm consisted of a mock competitive-reaction-time-task played against a fictional opponent with preprogrammed win- and lose-trials. In lose-trials, participants were provoked by subtraction of an amount of money between 0 and 90 cents. As a manipulation check, provocation induced a significant rise in behavioral aggression levels linked with an increased activation in the anterior cingulate cortex (ACC). High externalization predicted reduced ACC responses to provocation. However, high externalizing participants did not behave more aggressively than the low externalization group. Additionally, the high externalizing group showed a significantly lower positive affect while no group differences emerged for negative affect. In conclusion, high externalization in the non-clinical range was related to neural alterations in regions involved in affective decision-making as well as to changes in affect but did not lead to higher behavioral aggression levels in response to the mTAP. This is in line with previous findings suggesting that aberrations at multiple levels are essential for developing externalizing disorders.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CALLOUS-UNEMOTIONAL TRAITS; ANTERIOR CINGULATE CORTEX; ANTISOCIAL-BEHAVIOR; SUBSTANCE USE; CHILDREN; ADOLESCENTS; PSYCHOPATHOLOGY; PERSONALITY; ACTIVATION; DISORDERS; Taylor Aggression Paradigm; Externalizing spectrum; fMRI; Anterior cingulate cortex |
| Subjects: | 100 Philosophy & psychology > 150 Psychology |
| Divisions: | Human Sciences > Institut für Psychologie > Lehrstuhl für Psychologie VII (Medizinische Psychologie, Psychologische Diagnostik und Methodenlehre) - Prof. Dr. Brigitte Kudielka |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Feb 2024 14:58 |
| Last Modified: | 05 Feb 2024 14:58 |
| URI: | https://pred.uni-regensburg.de/id/eprint/57529 |
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