Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M-a case report

Goett, Hanna and Kiez, Silke and Dohmen, Hildegard and Kolodziej, Malgorzata and Stein, Marco (2022) Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M-a case report. CHILDS NERVOUS SYSTEM, 38 (9). pp. 1791-1796. ISSN 0256-7040, 1433-0350

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Abstract

Since high grade gliomas are aggressive brain tumors, intensive search for new treatment options is ongoing. For adult patients with newly diagnosed (ndGBM) and recurrent glioblastoma (rGBM), low intensity intermediate frequency alternating electric fields, known as tumor treating fields (TTFields) have been established as a new treatment modality. Tumor treating fields significantly increase survival rates in combination with adjuvant temozolomide (TMZ) in adult and GBM patients. Here, we report about feasibility and safety of treatment on a pediatric patient with diffuse midline glioma who is receiving TTFields therapy in combination with temozolomide.

Item Type: Article
Uncontrolled Keywords: PEDIATRIC HIGH-GRADE; TTFIELDS; BRAIN; MUTATIONS; SUBGROUPS; H3F3A; Glioblastoma; Glioma; Diffuse midline glioma; TTFields; Pediatric glioma
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Feb 2024 13:09
Last Modified: 06 Feb 2024 13:09
URI: https://pred.uni-regensburg.de/id/eprint/57625

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