Stokkel, Laura E. and van de Kamp, Maaike W. and Schaake, Eva E. and Boellaard, Thierry Nicolas and Hendricksen, Kees and van Rhijn, Bas W. G. and Mertens, Laura S. (2022) Robot-Assisted Partial Cystectomy versus Open Partial Cystectomy for Patients with Urachal Cancer. UROLOGIA INTERNATIONALIS, 106 (8). pp. 840-847. ISSN 0042-1138, 1423-0399
Full text not available from this repository. (Request a copy)Abstract
Introduction: Localized urachal cancer (UrC) can be treated with an open partial cystectomy (OPC) with en bloc resection of the urachal remnant and umbilicus. Robot-assisted partial cystectomy (RAPC) is an alternative approach, of which its safety and efficacy for UrC remains to be determined. In the present study, we analyze these outcomes after RAPC, compared with OPC. Methods: We retrospectively evaluated 55 cN0M0 UrC patients who underwent RAPC (n = 8) or OPC (n = 47) between 1994 and 2020. Overall survival (OS) and recurrence-free survival (RFS) were assessed using Kaplan-Meier methods. Positive surgical margins (PSM), port-site recurrences (PSR) versus wound recurrences were compared. Complications were recorded using the Clavien-Dindo classification. Results: Median follow-up was 40 months (IQR 21-95). Two-year OS and RFS for RAPC were 73% (95% confidence intervals (CI); 56-89 months) and 60% (95% CI; 42-78 months), respectively, versus 90% (95% CI; 85-95 months) and 66% (95% CI; 59-73 months) for OPC. PSM rate was 13% in both groups. PSR occurred in 2/8 (25%) patients after RAPC. No wound recurrences occurred after OPC. Postoperative complications occurred in 2/8 (25%) patients after RAPC, versus 5/47 (11%) after OPC (p = 0.27). Conclusion: Both RAPC and OPC seem feasible surgical modalities to treat localized UrC with comparable survival. The PSR rate of 25% after RAPC should prompt us to be cautious to recommend RAPC as no such recurrences were seen using OPC.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PORT-SITE METASTASES; LAPAROSCOPY; CARCINOMA; RESECTION; BLADDER; Urachus; Urachal carcinoma; Partial cystectomy; Therapy; Robotic surgery |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Feb 2024 06:29 |
| Last Modified: | 27 Feb 2024 06:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/57833 |
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