Borchers, Josephin and Merle, Cordula Leonie and Schoeneborn, Deborah Diana and Lyko, Lea Ronja and Thouet, Thomas and Wolfarth, Bernd and Kottmann, Tanja and Scheibenbogen, Carmen and Zimmer, Jeannot and Diederich, Sven and Bauer, Katrin and Sack, Ulrich and Schmalz, Gerhard and Ziebolz, Dirk and Wuestenfeld, Jan (2022) Salivary Diagnostic for Monitoring Strenuous Exercise-A Pilot Study in a Cohort of Male Ultramarathon Runners. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 19 (23): 16110. ISSN , 1660-4601
Full text not available from this repository. (Request a copy)Abstract
Intense physical stress, such as that in ultramarathon running, affects the immune system. For monitoring in sports medicine, non-invasive methods, e.g., salivary analysis, are of interest. This pilot cohort study aimed to assess changes in salivary parameters in response to an ultramarathon. The results were compared to blood parameters. Male, healthy finishers (n = 9, mean age: 48 +/- 8.8 years, mean height: 1.8 +/- 0.1 m, mean weight: 72.5 +/- 7.2 kg, mean BMI: 23.5 +/- 1.9 kg/cm(2)) of a 160 km ultramarathon were included. Saliva and blood samples were collected at three time points: T1 (baseline), T2 (shortly after the ultramarathon) and T3 (after recovery). In saliva, cortisol, testosterone, IL-1 beta, IL-6, IL-8, IL-10, TNF-alpha, albumin, IgA, alpha-amylase, aMMP-8, and neopterin were assessed via ELISA. In blood, cortisol, testosterone, IL-1 beta, IL-6, IL-8, IL-10, TNF-alpha, blood cell counts, procalcitonin, CRP, osmolality, albumin, and alpha-amylase were analyzed. The statistical evaluation comprised longitudinal testing and cross-sectional testing between saliva and blood using ratios of T2 and T3 to baseline values. Various parameters in saliva and blood changed in response to the ultramarathon. Comparing blood and saliva, the longitudinal changes of testosterone (p = 0.02) and alpha-amylase (p = 0.03) differed significantly. Despite the limitations of the study, it underlines that saliva is an interesting option for comprehensive monitoring in sports medicine and necessitates further studies.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | COMMITTEE CONSENSUS STATEMENT; IMMUNOGLOBULIN-A; ULTRA-MARATHON; ALPHA-AMYLASE; CORTISOL; SPORT; SERUM; INTERLEUKIN-6; BIOMARKERS; RESPONSES; endurance; saliva; immunoglobulin; inflammation; cytokines; biomarkers |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Zahnärztliche Prothetik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Feb 2024 14:15 |
| Last Modified: | 27 Feb 2024 14:15 |
| URI: | https://pred.uni-regensburg.de/id/eprint/57973 |
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