Knoedler, Samuel and Knoedler, Leonard and Baecher, Helena and Kauke-Navarro, Martin and Obed, Doha and Hoch, Cosima C. and Diehm, Yannick F. and Vosler, Peter S. and Harreus, Ulrich and Kneser, Ulrich and Panayi, Adriana C. (2022) 30-Day Postoperative Outcomes in Adults with Obstructive Sleep Apnea Undergoing Upper Airway Surgery. JOURNAL OF CLINICAL MEDICINE, 11 (24): 7371. ISSN , 2077-0383
Full text not available from this repository. (Request a copy)Abstract
Background: Obstructive sleep apnea (OSA) is a chronic disorder of the upper airway. OSA surgery has oftentimes been researched based on the outcomes of single-institutional facilities. We retrospectively analyzed a multi-institutional national database to investigate the outcomes of OSA surgery and identify risk factors for complications. Methods: We reviewed the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database (2008-2020) to identify patients who underwent OSA surgery. The postoperative outcomes of interest included 30-day surgical and medical complications, reoperation, readmission, and mortality. Additionally, we assessed risk-associated factors for complications, including comorbidities and preoperative blood values. Results: The study population included 4662 patients. Obesity (n = 2909; 63%) and hypertension (n = 1435; 31%) were the most frequent comorbidities. While two (0.04%) deaths were reported within the 30-day postoperative period, the total complication rate was 6.3% (n = 292). Increased BMI (p = 0.01), male sex (p = 0.03), history of diabetes (p = 0.002), hypertension requiring treatment (p = 0.03), inpatient setting (p < 0.0001), and American Society of Anesthesiology (ASA) physical status classification scores >= 4 (p < 0.0001) were identified as risk-associated factors for any postoperative complications. Increased alkaline phosphatase (ALP) was identified as a risk-associated factor for the occurrence of any complications (p = 0.02) and medical complications (p = 0.001). Conclusions: OSA surgery outcomes were analyzed at the national level, with complications shown to depend on AP levels, male gender, extreme BMI, and diabetes mellitus. While OSA surgery has demonstrated an overall positive safety profile, the implementation of these novel risk-associated variables into the perioperative workflow may further enhance patient care.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PERIOPERATIVE MANAGEMENT; ALKALINE-PHOSPHATASE; RISK-FACTORS; TRACHEOSTOMY; COMPLICATIONS; MORTALITY; CLASSIFICATION; POPULATION; CARE; obstructive sleep apnea (OSA); airway surgery; head and neck surgery; big data |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Feb 2024 14:41 |
| Last Modified: | 29 Feb 2024 14:41 |
| URI: | https://pred.uni-regensburg.de/id/eprint/58212 |
Actions (login required)
 |
View Item |
