Poslednik, Krzysztof B. and Czerwaty, Katarzyna and Ludwig, Nils and Molinska-Glura, Marta and Jablonska-Pawlak, Anna and Miskiewicz, Piotr and Kantor, Ireneusz and Dzaman, Karolina and Cyran, Anna M. and Szczepanski, Miroslaw J. (2022) Treatment Results of Endoscopic Transnasal Orbital Decompression for Graves' Orbitopathy-A Single-Center Retrospective Analysis in 28 Orbits of 16 Patients. JOURNAL OF PERSONALIZED MEDICINE, 12 (10): 1714. ISSN , 2075-4426
Full text not available from this repository. (Request a copy)Abstract
Graves' orbitopathy (GO) is an extrathyroidal manifestation of Graves' disease (GD), which can be associated with corneal ulcerations or optic neuropathy in severe forms. Transnasal endoscopic orbital decompression (TEOD) is a surgical procedure performed in order to decrease the intraorbital pressure by removing part of its bony borders in cases with excessive mass in orbit. The aim of this study was to present the results and evaluate the efficacy of TEOD for GO. The retrospective study included 28 orbits (16 patients) who underwent TEOD from 2017 to 2020. Outcome was evaluated based on visual acuity improvement, clinical activity score (CAS) decrease, proptosis, and intraocular pressure (IOP) reduction. A preoperative best-corrected visual acuity (BCVA) increased from 0.69 +/- 0.385 (mean +/- standard deviation) to 0.74 +/- 0.332 (p = 0.17) postoperatively. CAS decreased in 15 orbits postoperatively. Proptosis decreased from 22.89 +/- 1.873 mm to 21.25 +/- 2.053 mm (p < 0.05). IOP decreased from a preoperative 16.11 +/- 3.93 mmHg to 14.40 +/- 3.27 mmHg (p < 0.05) postoperatively. In addition, postoperative relief of exposure keratitis was observed. The analysis of development of iatrogenic diplopia revealed increasing in degree of diplopia. TEOD shows rare complications, but significant improvements in BCVA, CAS, proptosis, and IOP.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INTRAOCULAR-PRESSURE; OPTIC NEUROPATHY; MANAGEMENT; REDUCTION; endoscopic transnasal orbital decompression; Graves' orbitopathy; dysthyroid optic neuropathy; compressive optic neuropathy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Feb 2024 06:38 |
| Last Modified: | 02 Feb 2024 06:38 |
| URI: | https://pred.uni-regensburg.de/id/eprint/58319 |
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