Hengstenberg, Christian and Condado, Jose and Garcia, David and Marin Martinez, Milka and La Forgia, Giambattista and Ebner, Adrian and Gallo, Santiago and Silva, Enrique and Holzamer, Andreas and Husser, Oliver and Hilker, Michael (2015) TRINITY heart valve prosthesis: a novel repositionable and retrievable transapical transcatheter aortic valve system. EUROINTERVENTION, 10 (11). pp. 1332-1335. ISSN 1774-024X, 1969-6213
Full text not available from this repository. (Request a copy)Abstract
Aims: Transcatheter aortic valve implantation (TAVI) has become a viable option for selected high-risk patients with severe and symptomatic aortic stenosis. First- and second-generation TAVI devices are either self- or balloon-expandable, and are often not repositionable or not fully retrievable, leading to suboptimal positioning in some cases. This may result in paravalvular regurgitation, AV conduction delay, or compromise of coronary perfusion. A broader application of TAVI requires advances in both valve and delivery systems. Therefore, in order to facilitate accurate positioning, to minimise paravalvular leakage, possibly to reduce the risk of AV conduction delay, and possibly to be able to abort the procedure, a "next-generation" TAVI system has been developed which is repositionable and retrievable, the TRINITY heart valve system. Methods and results: The TRINITY heart valve system was implanted in a first-in-human study using the transapical approach to demonstrate feasibility and procedural success. All endpoints were adjudicated according to VARC definitions at seven and 30 days. The TRINITY heart valve system was implanted in a 74-year-old patient with severe symptomatic aortic valve stenosis. In this case, repositioning of the TRINITY resulted in optimal position without paravalvular leakage and with perfect function. Conclusions: The TRINITY heart valve is a repositionable and retrievable TAVI system. Both the implantation result and short-term clinical and haemodynamic outcome were excellent.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | REPLACEMENT; OUTCOMES; DEFINITIONS; aortic stenosis; self-expandable valve; transcatheter aortic valve implantation; Transcatheter aortic valve replacement; TRINITY heart valve system |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 24 Jul 2019 08:03 |
| Last Modified: | 24 Jul 2019 08:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/5832 |
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