Molecular diagnostics in neuropathology

Dietmaier, W. and Lorenz, J. and Riemenschneider, M. J. (2015) Molecular diagnostics in neuropathology. PATHOLOGE, 36 (2). pp. 171-180. ISSN 0172-8113, 1432-1963

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Abstract

As in only few other areas of oncology, molecular markers in neurooncology have become an integral part of clinical decision-making. This development is driven by a bustling scientific activity exploring the molecular basis and pathogenesis of human brain tumors. In addition, a high percentage of brain tumor patients are included in clinical studies in which molecular markers are assessed and linked with clinical informativeness. First steps towards more differentiated therapeutic strategies against brain tumors have thus been taken. The implementation in the clinical and diagnostic routine requires a detailed knowledge and a close collaboration between all medical disciplines involved.

Item Type: Article
Uncontrolled Keywords: MGMT PROMOTER METHYLATION; PILOCYTIC ASTROCYTOMAS; ANAPLASTIC GLIOMAS; PHASE-3 TRIAL; IDH1 MUTATION; GLIOBLASTOMA; TEMOZOLOMIDE; MEDULLOBLASTOMA; RADIOTHERAPY; AMPLIFICATION; Glioma; MGMT; 1p/19q; IDH1/2; Pediatric brain tumors
Divisions: Medicine > Abteilung für Neuropathologie
Medicine > Lehrstuhl für Pathologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Jul 2019 10:49
Last Modified: 24 Jul 2019 10:49
URI: https://pred.uni-regensburg.de/id/eprint/5839

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