Sex Differences in Comorbidity Combinations in the Swedish Population

Basso, Laura and Boecking, Benjamin and Neff, Patrick and Brueggemann, Petra and Cederroth, Christopher R. and Rose, Matthias and Mazurek, Birgit (2022) Sex Differences in Comorbidity Combinations in the Swedish Population. BIOMOLECULES, 12 (7): 949. ISSN , 2218-273X

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Abstract

High comorbidity rates, especially mental-physical comorbidity, constitute an increasing health care burden, with women and men being differentially affected. To gain an overview of comorbidity rates stratified by sex across a range of different conditions, this study examines comorbidity patterns within and between cardiovascular, pulmonary, skin, endocrine, digestive, urogenital, musculoskeletal, neurological diseases, and psychiatric conditions. Self-report data from the LifeGene cohort of 31,825 participants from the general Swedish population (62.5% female, 18-84 years) were analyzed. Pairwise comorbidity rates of 54 self-reported conditions in women and men and adjusted odds ratios (ORs) for their comparison were calculated. Overall, the rate of pairwise disease combinations with significant comorbidity was higher in women than men (14.36% vs. 9.40%). Among psychiatric conditions, this rate was considerably high, with 41.76% in women and 39.01% in men. The highest percentages of elevated mental-physical comorbidity in women were found for musculoskeletal diseases (21.43%), digestive diseases (20.71%), and skin diseases (13.39%); in men, for musculoskeletal diseases (14.29%), neurological diseases (11.22%), and digestive diseases (10%). Implications include the need for integrating mental and physical health care services and a shift from a disease-centered to an individualized, patient-centered focus in clinical care.

Item Type: Article
Uncontrolled Keywords: IRRITABLE-BOWEL-SYNDROME; ADVERSE CHILDHOOD EXPERIENCES; QUALITY-OF-CARE; MENTAL-HEALTH; SOCIOECONOMIC-STATUS; GENERAL-POPULATION; ANXIETY DISORDERS; PHYSICAL ILLNESS; EXCESS MORTALITY; SHOULDER PAIN; comorbidity; health; sex; diseases; psychiatric; digestive; musculoskeletal; skin; neurological
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 01 Feb 2024 10:57
Last Modified: 01 Feb 2024 10:57
URI: https://pred.uni-regensburg.de/id/eprint/58440

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