Lebentrau, Steffen and Wolff, Ingmar and Hempel, Marie Christine and Haccius, Marlene and Kluth, Luis A. and Pycha, Armin and Brookman-May, Sabine and Schneider, Till Rasmus and Hermanns, Thomas and Distler, Florian A. and Boegemann, Martin and Kuebler, Hubert and Shariat, Shahrokh F. and Burger, Maximilian and May, Matthias (2022) Knowledge of German-speaking urologists regarding the association between penile cancer and human papilloma virus: results of a survey of the European PROspective Penile Cancer Study (E-PROPS). AKTUELLE UROLOGIE, 53 (05). pp. 461-467. ISSN 0001-7868, 1438-8820
Full text not available from this repository. (Request a copy)Abstract
Background A recent meta-analysis showed that penile cancer (PeC) is associated with the human papilloma virus (HPV) in 50 % of patients in Europe. It is unknown whether urologists are aware of the impact of viral carcinogenesis. Methods A (German-language) survey comprising 14 items was created and sent to urologists of 45 clinical centres in Germany (n = 34), Austria (n = 8), Switzerland (n = 2) and Italy/South Tyrol (n = 1) once in Q3/2018. According to a predefined quality standard, a total of 557 surveys were eligible for final data analysis (response rate: 85.7 %). Among other questions, urologists were asked to state the frequency of HPV-associated PeC in Europe. 4 potential answers were provided: (A)-"< 25 %", (B)-"25 - 50 %", (C)-"> 50 - 75 %", (D)-"level of association unknown". For the final calculation, a tolerance of +/- 50 % was considered acceptable, so B and C were deemed correct answers. Based on a bootstrap-adjusted multivariate logistic regression model, criteria independently predicting a correct answer were identified. Results Categories A-D were selected in 19.2 % (n = 107), 48.8 % (n = 272), 12.9 % (n = 72) and 19 % (n = 106), respectively, representing a rate of 61.8 % of urologists (n = 344) reaching the endpoint (B + C). Autonomous performance of chemotherapy for PeC by urologists within the given centre (OR 1.55, p[Bootstrap] = 0.036) and the centre's number of urological beds (OR 1.02, p[Bootstrap] = 0.025) were the only parameters showing a significant independent impact on the endpoint. In contrast, the status of a university centre (p = 0.143), a leading position of the responding urologist (p = 0.375) and the number of PeC patients treated per year and centre (p = 0.571) did not significantly predict a correct answer. Conclusions Our results demonstrate insufficient knowledge on the association of PeC and HPV among German-speaking urologists.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GUIDELINES; questionnaire; viral carcinogenesis; squamous cell carcinoma of the penis; level of knowledge; independent predictors |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Feb 2024 06:56 |
| Last Modified: | 01 Feb 2024 06:56 |
| URI: | https://pred.uni-regensburg.de/id/eprint/58565 |
Actions (login required)
 |
View Item |
