Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022

Snowden, John A. and Sanchez-Ortega, Isabel and Corbacioglu, Selim and Basak, Grzegorz W. and Chabannon, Christian and de la Camara, Rafael and Dolstra, Harry and Duarte, Rafael F. and Glass, Bertram and Greco, Raffaella and Lankester, Arjan C. and Mohty, Mohamad and Neven, Benedicte and de Latour, Regis Peffault and Pedrazzoli, Paolo and Peric, Zinaida and Yakoub-Agha, Ibrahim and Sureda, Anna and Kroeger, Nicolaus (2022) Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022. BONE MARROW TRANSPLANTATION, 57 (8). pp. 1217-1239. ISSN 0268-3369, 1476-5365

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Abstract

For over two decades, the EBMT has updated recommendations on indications for haematopoietic cell transplantation (HCT) practice based on clinical and scientific developments in the field. This is the eighth special EBMT report on the indications for HCT for haematological diseases, solid tumours and immune disorders. Our aim is to provide general guidance on HCT indications according to prevailing clinical practice in EBMT countries and centres. In order to inform patient decisions, these recommendations must be considered in conjunction with the risk of the disease, risk of HCT procedure and non-transplant strategies, including evolving cellular therapies. HCT techniques are constantly evolving and we make no specific recommendations, but encourage harmonisation of practice, where possible, to ensure experience across indications can be meaningfully aggregated via registry outputs. We also recommend working according to JACIE accreditation standards to maintain quality in clinical and laboratory components of practice, including benchmarking of survival outcomes. Since the last edition, the COVID-19 pandemic has affected clinical decision making and activity across indications. Although the full impact of the pandemic is yet to be determined, we recommend that decision making across indications is delivered with ongoing reference to EBMT and national COVID-19 guidance, in accordance with current local conditions.

Item Type: Article
Uncontrolled Keywords: ACUTE LYMPHOBLASTIC-LEUKEMIA; HIGH-DOSE CHEMOTHERAPY; MINIMAL RESIDUAL DISEASE; SEVERE APLASTIC-ANEMIA; UNRELATED DONOR TRANSPLANTATION; BONE-MARROW-TRANSPLANTATION; LYMPHOMA WORKING PARTY; ACUTE MYELOID-LEUKEMIA; CORD BLOOD TRANSPLANTATION; LONG-TERM OUTCOMES;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Dec 2023 07:38
Last Modified: 14 Dec 2023 07:38
URI: https://pred.uni-regensburg.de/id/eprint/58673

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