Anti-SARS-CoV-2 vaccination in people with multiple sclerosis: Lessons learnt a year in

Pugliatti, Maura and Hartung, Hans-Peter and Oreja-Guevara, Celia and Pozzilli, Carlo and Airas, Laura and Alkhawajah, Mona and Grigoriadis, Nikolaos and Magyari, Melinda and Van Wijmeersch, Bart and Zakaria, Magd and Linker, Ralf and Chan, Andrew and Vermersch, Patrick and Berger, Thomas (2022) Anti-SARS-CoV-2 vaccination in people with multiple sclerosis: Lessons learnt a year in. FRONTIERS IN IMMUNOLOGY, 13: 1045101. ISSN 1664-3224,

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Abstract

It has been over a year since people with multiple sclerosis (pwMS) have been receiving vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With a negligible number of cases in which vaccination led to a relapse or new onset MS, experts around the world agree that the potential consequences of COVID-19 in pwMS by far outweigh the risks of vaccination. This article reviews the currently available types of anti-SARS-CoV-2 vaccines and the immune responses they elicit in pwMS treated with different DMTs. Findings to date highlight the importance of vaccine timing in relation to DMT dosing to maximize protection, and of encouraging pwMS to get booster doses when offered.

Item Type: Article
Uncontrolled Keywords: VACCINES; COVID-19; vaccines; SARS-CoV-2; multiple sclerosis; disease modifying therapies; immune response; adverse events
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurologie
Depositing User: Petra Gürster
Date Deposited: 05 Sep 2023 10:59
Last Modified: 05 Sep 2023 10:59
URI: https://pred.uni-regensburg.de/id/eprint/58735

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