Combes, Alain and Brodie, Daniel and Aissaoui, Nadia and Bein, Thomas and Capellier, Gilles and Dalton, Heidi J. and Diehl, Jean-Luc and Kluge, Stefan and McAuley, Daniel F. and Schmidt, Matthieu and Slutsky, Arthur S. and Jaber, Samir (2022) Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions. INTENSIVE CARE MEDICINE, 48 (10). pp. 1308-1321. ISSN 0342-4642, 1432-1238
Full text not available from this repository. (Request a copy)Abstract
Extracorporeal carbon dioxide removal (ECCO2R) is a form of extracorporeal life support (ECLS) largely aimed at removing carbon dioxide in patients with acute hypoxemic or acute hypercapnic respiratory failure, so as to minimize respiratory acidosis, allowing more lung protective ventilatory settings which should decrease ventilator-induced lung injury. ECCO2R is increasingly being used despite the lack of high-quality evidence, while complications associated with the technique remain an issue of concern. This review explains the physiological basis underlying the use of ECCO2R, reviews the evidence regarding indications and contraindications, patient management and complications, and addresses organizational and ethical considerations. The indications and the risk-to-benefit ratio of this technique should now be carefully evaluated using structured national or international registries and large randomized trials.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | THERAPY CRRT CARE; MEMBRANE-OXYGENATION; LIFE-SUPPORT; CO2 REMOVAL; MECHANICAL VENTILATION; DISTRESS-SYNDROME; NONINVASIVE VENTILATION; PROTECTIVE VENTILATION; LUNG TRANSPLANTATION; QUALITY INDICATORS; Acute respiratory failure; Extracorporeal carbon dioxide removal; Mechanical ventilation; Outcome |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 05 Sep 2023 10:54 |
| Last Modified: | 05 Sep 2023 10:54 |
| URI: | https://pred.uni-regensburg.de/id/eprint/58767 |
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