Peters, Annette and Greiser, Karin Halina and Goettlicher, Susanne and Ahrens, Wolfgang and Albrecht, Maren and Bamberg, Fabian and Baernighausen, Till and Becher, Heiko and Berger, Klaus and Beule, Achim and Boeing, Heiner and Bohn, Barbara and Bohnert, Kerstin and Braun, Bettina and Brenner, Hermann and Buelow, Robin and Castell, Stefanie and Damms-Machado, Antje and Doerr, Marcus and Ebert, Nina and Ecker, Margit and Emmel, Carina and Fischer, Beate and Franzke, Claus-Werner and Gastell, Sylvia and Giani, Guido and Guenther, Matthias and Guenther, Kathrin and Guenther, Klaus-Peter and Haerting, Johannes and Haug, Ulrike and Heid, Iris M. and Heier, Margit and Heinemeyer, Diana and Hendel, Thomas and Herbolsheimer, Florian and Hirsch, Jochen and Hoffmann, Wolfgang and Holleczek, Bernd and Hoelling, Heike and Hoerlein, Andreas and Joeckel, Karl-Heinz and Kaaks, Rudolf and Karch, Andre and Karrasch, Stefan and Kartschmit, Nadja and Kauczor, Hans-Ulrich and Keil, Thomas and Kemmling, Yvonne and Klee, Bianca and Klueppelholz, Birgit and Kluttig, Alexander and Kofink, Lisa and Koettgen, Anna and Kraft, Daniel and Krause, Gerard and Kretz, Lisa and Krist, Lilian and Kuehnisch, Jan and Kuss, Oliver and Legath, Nicole and Lehnich, Anna-Therese and Leitzmann, Michael and Lieb, Wolfgang and Linseisen, Jakob and Loeffler, Markus and Macdonald, Anke and Maier-Hein, Klaus H. and Mangold, Nina and Meinke-Franze, Claudia and Meisinger, Christa and Melzer, Juliane and Mergarten, Bjorn and Michels, Karin B. and Mikolajczyk, Rafael and Moebus, Susanne and Mueller, Ulrich and Nauck, Matthias and Niendorf, Thoralf and Nikolaou, Konstantin and Obi, Nadia and Ostrzinski, Stefan and Panreck, Leo and Pigeot, Iris and Pischon, Tobias and Pschibul-Thamm, Irene and Rathmann, Wolfgang and Reineke, Achim and Roloff, Stefanie and Rujescu, Dan and Rupf, Stefan and Sander, Oliver and Schikowski, Tamara and Schipf, Sabine and Schirmacher, Peter and Schlett, Christopher L. and Schmidt, Borge and Schmidt, Georg and Schmidt, Martin and Schoene, Gina and Schulz, Holger and Schulze, Matthias B. and Schweig, Alexandra and Sedlmeier, Anja M. and Selder, Sonja and Six-Merker, Julia and Sowade, Ramona and Stang, Andreas and Stegle, Oliver and Steindorf, Karen and Stubs, Gunthard and Swart, Enno and Teismann, Henning and Thiele, Inke and Thierry, Sigrid and Ueffing, Marius and Voelzke, Henry and Waniek, Sabina and Weber, Andrea and Werner, Nicole and Wichmann, H-Erich and Willich, Stefan N. and Wirkner, Kerstin and Wolf, Kathrin and Wolff, Robert and Zeeb, Hajo and Zinkhan, Melanie and Zschocke, Johannes (2022) Framework and baseline examination of the German National Cohort (NAKO). EUROPEAN JOURNAL OF EPIDEMIOLOGY, 37 (10). pp. 1107-1124. ISSN 0393-2990, 1573-7284
Full text not available from this repository.Abstract
The German National Cohort (NAKO) is a multidisciplinary, population-based prospective cohort study that aims to investigate the causes of widespread diseases, identify risk factors and improve early detection and prevention of disease. Specifically, NAKO is designed to identify novel and better characterize established risk and protection factors for the development of cardiovascular diseases, cancer, diabetes, neurodegenerative and psychiatric diseases, musculoskeletal diseases, respiratory and infectious diseases in a random sample of the general population. Between 2014 and 2019, a total of 205,415 men and women aged 19-74 years were recruited and examined in 18 study centres in Germany. The baseline assessment included a face-to-face interview, self-administered questionnaires and a wide range of biomedical examinations. Biomaterials were collected from all participants including serum, EDTA plasma, buffy coats, RNA and erythrocytes, urine, saliva, nasal swabs and stool. In 56,971 participants, an intensified examination programme was implemented. Whole-body 3T magnetic resonance imaging was performed in 30,861 participants on dedicated scanners. NAKO collects follow-up information on incident diseases through a combination of active follow-up using self-report via written questionnaires at 2-3 year intervals and passive follow-up via record linkages. All study participants are invited for re-examinations at the study centres in 4-5 year intervals. Thereby, longitudinal information on changes in risk factor profiles and in vascular, cardiac, metabolic, neurocognitive, pulmonary and sensory function is collected. NAKO is a major resource for population-based epidemiology to identify new and tailored strategies for early detection, prediction, prevention and treatment of major diseases for the next 30 years.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | QUALITY-ASSURANCE; DESIGN; BIOBANK; IMPACT; TESTS; NOISE; Population-based cohort; Non-communicable diseases; Communicable diseases; Epidemiology; Life-style and socio-economic factors; Magnetic resonance imaging; Pre-clinical disease; Functional impairments; Psychosocial factors |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Dec 2023 11:17 |
| Last Modified: | 12 Dec 2023 11:17 |
| URI: | https://pred.uni-regensburg.de/id/eprint/58771 |
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