Kandsperger, Stephanie and Brunner, Romuald and Rupprecht, Rainer and Baghai, Thomas C. (2023) Depressive Störungen in der Adoleszenz: Aktuelle Studienlage zur Mikrobiota-Darm-Hirn-Achse = Depressive Disorders in Adolescence: Current State of Studies Concerning the Microbiota-Gut-Brain Axis. ZEITSCHRIFT FUR KINDER-UND JUGENDPSYCHIATRIE UND PSYCHOTHERAPIE, 51 (6). pp. 419-428. ISSN 1422-4917, 1664-2880
Full text not available from this repository. (Request a copy)Abstract
Depressive disorders increase during adolescence and often lead to significant impairment in affected individuals - despite treatment. Current research efforts aim to further investigate the pathophysiology of depression, considering the influence of gut microbiota on the gut-brain axis. The present narrative review outlines the current state of studies of the microbiota-gut-brain axis in depressive disorders as well as the direct and indirect interactions in adolescence. Besides providing promising results from animal studies, studies on the microbiota-gutbrain axis in adults suffering from depressive disorders are growing steadily. In depressed adolescents, however, the study situation is still marginal, making a recommendation for the supplementation of probiotics and prebiotics in depressed children and adolescents impossible according to the current state of research. Against the background of a very limited number of studies involving adolescents with depressive disorders, the interactive role of the microbiota-gut-brain axis in adolescent development should receive special attention in future research projects.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MENTAL-DISORDERS; HEALTH; PSYCHOBIOTICS; DEFINITION; PREVALENCE; PROBIOTICS; PREDICTOR; ADULTHOOD; CORTISOL; CHILDREN; depressive disorders; microbiota-gut-brain axis; probiotics; prebiotics; adolescence |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie Medicine > Lehrstuhl für Kinder- und Jugendpsychiatrie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Feb 2024 07:36 |
| Last Modified: | 22 Feb 2024 07:36 |
| URI: | https://pred.uni-regensburg.de/id/eprint/59009 |
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