The Use of Contrast-Enhanced Sonography for Therapy Monitoring of Metastatic Lymph Nodes: A Systematic Review

Rink, Maximilian and Jung, Ernst-Michael and Kuenzel, Julian (2023) The Use of Contrast-Enhanced Sonography for Therapy Monitoring of Metastatic Lymph Nodes: A Systematic Review. CURRENT ONCOLOGY, 30 (7). pp. 6734-6743. ISSN 1198-0052, 1718-7729

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Abstract

Metastatic cervical lymph nodes are a frequent finding in head and neck squamous cell carcinoma (HNSCC). If a non-surgical approach is primarily chosen, a therapy response evaluation of the primary tumor and the affected lymph nodes is necessary in the follow-up. Supplementary contrast-enhanced ultrasound (CEUS) can be used to precisely visualize the microcirculation of the target lesion in the neck, whereby malignant and benign findings differ in their uptake behavior. The same applies to many other solid tumors. For various tumor entities, it has already been shown that therapy monitoring is possible through regular contrast-enhanced sonography of the primary tumor or the affected lymph nodes. Thus, in some cases, maybe in the future, a change in therapy strategy can be achieved at an early stage in the case of non-response or, in the case of therapy success, a de-escalation of subsequent (surgical) measures can be achieved. In this paper, a systematic review of the available studies and a discussion of the potential of therapy monitoring by means of CEUS in HNSCC are presented.

Item Type: Article
Uncontrolled Keywords: SQUAMOUS-CELL CARCINOMA; NEOADJUVANT CHEMOTHERAPY; CLINICAL-PRACTICE; EARLY PREDICTION; ULTRASOUND CEUS; HEAD; CANCER; ULTRASONOGRAPHY; RISK; RADIOTHERAPY; contrast-enhanced ultrasound; CEUS; therapy monitoring; solid carcinoma; head and neck squamous carcinoma; lymph node metastasis
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 27 Feb 2024 10:55
Last Modified: 27 Feb 2024 10:55
URI: https://pred.uni-regensburg.de/id/eprint/59106

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