Bruckschlegel, Christoph and Schlosser, Marc and Wongkaew, Nongnoot (2023) Investigating nanocatalyst-embedding laser-induced carbon nanofibers for non-enzymatic electrochemical sensing of hydrogen peroxide. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (18). pp. 4487-4499. ISSN 1618-2642, 1618-2650
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In this present study, we explored the catalytic behaviors of the in situ generated metal nanoparticles, i.e., Pt/Ni, embedded in laser-induced carbon nanofibers (LCNFs) and their potential for H2O2 detection under physiological conditions. Furthermore, we demonstrate current limitations of laser-generated nanocatalyst embedded within LCNFs as electrochemical detectors and possible strategies to overcome the issues. Cyclic voltammetry revealed the distinctive electrocatalytic behaviors of carbon nanofibers embedding Pt and Ni in various ratios. With chronoamperometry at +0.5 V, it was found that modulation of Pt and Ni content affected only current related to H2O2 but not other interfering electroactive substances, i.e., ascorbic acid (AA), uric acid (UA), dopamine (DA), and glucose. This implies that the interferences react to the carbon nanofibers regardless of the presence of metal nanocatalysts. Carbon nanofibers loaded only with Pt and without Ni performed best in H2O2 detection in phosphate-buffered solution with a limit of detection (LOD) of 1.4 mu M, a limit of quantification (LOQ) of 5.7 mu M, a linear range from 5 to 500 mu M, and a sensitivity of 15 mu A mM(-1) cm(-2). By increasing Pt loading, the interfering signals from UA and DA could be minimized. Furthermore, we found that modification of electrodes with nylon improves the recovery of H2O2 spiked in diluted and undiluted human serum. The study is paving the way for the efficient utilization of laser-generated nanocatalyst-embedding carbon nanomaterials for non-enzymatic sensors, which ultimately will lead to inexpensive point-of-need devices with favorable analytical performance.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GRAPHENE; ELECTRODE; PLATINUM; H2O2; NANOPARTICLES; SENSORS; Hydrogen peroxide detection; Non-enzymatic sensors; Electrochemical detection; Nanocatalysts; Laser-induced carbon nanofibers; Point-of-need devices |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik Chemistry and Pharmacy > Institut für Anorganische Chemie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 Feb 2024 06:52 |
| Last Modified: | 28 Feb 2024 06:52 |
| URI: | https://pred.uni-regensburg.de/id/eprint/59137 |
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