Biermann, Niklas and Taeger, Christian D. and Schatz, Valentin and Eigenberger, Andreas and Prantl, Lukas and Felthaus, Oliver (2023) The influence of negative pressure wound therapy on bacterial and fungal growth. JOURNAL OF TISSUE VIABILITY, 32 (4). pp. 613-617. ISSN 0965-206X, 1876-4746
Full text not available from this repository. (Request a copy)Abstract
Background: The use of negative pressure wound therapy (NPWT) in superinfected wounds is controversial. The mechanism of action is unclear, but recent studies have shown lower atmospheric oxygen levels within the dressing. Therefore, different oxygen-favoring bacteria and fungi might benefit or face impaired thriving attached to a standard NPWT-device. After 48 hours, colonies were separately harvested from the agar and foam. Optical density (OD) was obtained in order to Results: For all tested microorganisms, no overall significant differences were found compared to controls. Subanalysis showed lower OD levels from the agar beneath Conclusion: NPWT removed bacteria and fungi from the wound surface but accumulation is found within the foam. The use of NPWT showed no influence on bacterial or fungal growth selection. With superinfected wounds, the use of NPWT should thoroughly be evaluated as toxins and virulence factors may not fully be evacuated.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | VACUUM-ASSISTED CLOSURE; DRESSINGS; CULTURE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 30 Jan 2024 14:10 |
| Last Modified: | 30 Jan 2024 14:10 |
| URI: | https://pred.uni-regensburg.de/id/eprint/59236 |
Actions (login required)
 |
View Item |
