Trajectories of quality of life, return to work, psychopathology, and disability in survivors of the acute respiratory distress syndrome (ARDS): A three-year prospective cohort study (DACAPO)

Szymczak, Hermann and Dodoo-Schittko, Frank and Brandstetter, Susanne and Rohr, Magdalena and Blecha, Sebastian and Bein, Thomas and Apfelbacher, Christian (2023) Trajectories of quality of life, return to work, psychopathology, and disability in survivors of the acute respiratory distress syndrome (ARDS): A three-year prospective cohort study (DACAPO). JOURNAL OF CRITICAL CARE, 78: 154356. ISSN 0883-9441, 1557-8615

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Abstract

Purpose: Describe the long-term development of outcomes for survivors of the Acute Respiratory Distress Syn-drome (ARDS).Material and Methods: A cohort study with N = 877 ARDS survivors was conducted. Health related quality of life (HRQoL, Physical and Mental Component Scale: PCS, MCS of the SF-12), return to work (RtW), panic disorder, depressive symptoms (PHQ-D), and post-traumatic-stress-disorder (PTSD, PTSS-14) were assessed at 3, 6, 12, 24, and 36 months after discharge from ICU.Results: PCS, MCS, and RtW increased during the first 12 months [e.g. PCS: Md = 36 (IQR 31-43) at 3 months, Md = 42 (IQR 34-52) at 12 months; MCS: Md = 44 (IQR 32-54) at 3 months, Md = 47 (IQR 33-57) at 12 months, RtW = 23.2% at 3 months, 54.5% at 12 months], and remained relatively stable afterwards. Proportion of major depressive syndrome decreased from 3 (14.2%) to 36 months (8.9%). Proportions of panic disorder (5.3% to 7.4%) and PTSD (27.1% to 32.6%) varied only slightly.Conclusions: Most of recovery in HRQoL and RtW occur during the first 12 months, after which a plateau is reached, indicating a chronification for many patients. Contrary to this, however, psychopathological symptoms remain stable, except for depressive symptoms. [200 words].

Item Type: Article
Uncontrolled Keywords: POSTTRAUMATIC-STRESS-DISORDER; PATIENT HEALTH QUESTIONNAIRE; CRITICAL ILLNESS; DEPRESSIVE SYMPTOMS; RELIABILITY; VALIDATION; MORTALITY; INTERVIEW; ADULTS; SCORE; ARDS; Health related quality of life; Return to work; Psychopathology; Prospective cohort; Critical illness
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 31 Jan 2024 12:58
Last Modified: 31 Jan 2024 12:58
URI: https://pred.uni-regensburg.de/id/eprint/59247

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