Outcome of joint replacement in patients with underlying rheumatoid disease

Holzapfel, Dominik Emanuel and Thieme, Max and Kappenschneider, Tobias and Holzapfel, Sabrina and Maderbacher, Guenther and Weber, Markus and Grifka, Joachim and Meyer, Matthias (2023) Outcome of joint replacement in patients with underlying rheumatoid disease. ZEITSCHRIFT FUR RHEUMATOLOGIE, 82. pp. 825-833. ISSN 0340-1855, 1435-1250

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Abstract

Background: Artificial joint replacement is a meaningful treatment option for patients with advanced rheumatic degenerative joint diseases. The aim of this study was to investigate the influence of the underlying rheumatic diseases on postoperative complications and patient-reported outcome (PRO) after elective total joint replacement (TJR).Material and methods: In a retrospective analysis of 9149 patients with elective total knee or total hip arthroplasty (TKR and THR), complication rates and PRO of patients with and without rheumatic diseases (RD) were compared. Multivariate logistic regression models were used to determine whether the underlying rheumatic disease was an independent risk factor for various complications.Results: In the univariate analyses the RD patients had an increased risk of medical complications (7.1% vs. 5.2%; p = 0.028) and Clavien-Dindo grade IV complications (2.8% vs. 1.8%; p = 0.048) after TJR. This was confirmed in multivariate statistical analyses (p < 0.034). The rates for operative revisions and surgical complications were comparable (2.5% vs. 2.4%; p = 0.485). Analysis of the PRO showed a higher responder rate in patients with RD after TKR (91.9% vs. 84.5%, p = 0.039). In contrast, the responder rate in patients with RD after THR was comparable (93.4% vs. 93.2%, p = 0.584).Conclusion: Despite increased postoperative complication rates, patients with underlying rheumatic diseases showed a comparable outcome 1 year after TJR. After TKR the RD patients showed even higher responder rates. Although RD patients are a vulnerable patient group, they can still benefit from joint replacement.

Item Type: Article
Uncontrolled Keywords: RESPONDER CRITERIA; KNEE; ARTHRITIS; SURGERY; COHORT; RISK; SET; HIP; Total joint replacement; Patient-reported outcome; Postoperative complications; Total hip arthroplasty; Total knee arthroplasty
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Orthopädie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 19 Mar 2024 09:41
Last Modified: 19 Mar 2024 09:41
URI: https://pred.uni-regensburg.de/id/eprint/59827

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