Zaiss, Dietmar M. W. and Pearce, Edward J. and Artis, David and McKenzie, Andrew N. J. and Klose, Christoph S. N. (2024) Cooperation of ILC2s and T<sub>H</sub>2 cells in the expulsion of intestinal helminth parasites. NATURE REVIEWS IMMUNOLOGY, 24. pp. 294-302. ISSN 1474-1733, 1474-1741
Full text not available from this repository. (Request a copy)Abstract
Type 2 immune responses form a critical defence against enteric worm infections. In recent years, mouse models have revealed shared and unique functions for group 2 innate lymphoid cells and T helper 2 cells in type 2 immune response to intestinal helminths. Both cell types use similar innate effector functions at the site of infection, whereas each population has distinct roles during different stages of infection. In this Perspective, we review the underlying mechanisms used by group 2 innate lymphoid cells and T helper 2 cells to cooperate with each other and suggest an overarching model of the interplay between these cell types over the course of a helminth infection.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INNATE LYMPHOID-CELLS; CELLULAR IMMUNE-RESPONSES; TYPE-2 IMMUNITY; PROTECTIVE IMMUNITY; TUFT CELLS; T-CELLS; TRICHURIS-MURIS; MICE REVEAL; IL-13; RESISTANCE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Immunologie Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 May 2024 09:46 |
| Last Modified: | 14 May 2024 09:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/59847 |
Actions (login required)
 |
View Item |
