Contrast-Enhanced Ultrasound of Fibrolamellar Hepatocellular Carcinoma

Wildner, Dane and Schlitt, Hans Juergen and Baeuerle, Tobias and Haibach, Martina (2023) Contrast-Enhanced Ultrasound of Fibrolamellar Hepatocellular Carcinoma. ZEITSCHRIFT FUR GASTROENTEROLOGIE, 61 (12). pp. 1618-1622. ISSN 0044-2771, 1439-7803

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Abstract

We present the case of a 24-year-old male patient, who was admitted for endoscopy due to sustained pain in the upper abdomen with nausea and postprandial fullness without vomiting for more than 5 months. In the physical examination, an epigastric induration was found. Endoscopy revealed an external impression of the proximal duodenum. Beyond that, normal findings could be ascertained in gastroscopy and ileo-colonoscopy. Abdominal ultrasound identified a large hypoechoic lesion in the left liver lobe with a sharp delineation. Along the upper mesenteric vessels, enlarged lymphnodes were visible with contact to the proximal duodenum. Contrast-enhanced ultrasound (CE-US) was conducted and revealed the typical perfusion pattern of hepatocellular carcinoma. For further assessment, an ultrasound-guided core-biopsy of the lesion was performed. The histopathological evaluations resulted in the diagnosis of a hepatocellular carcinoma of fibrolamellar subtype.With the present case, we want to illustrate the perfusion pattern of a fibrolamellar hepatocellular carcinoma in contrast-enhanced ultrasound. Even though the tumor tissue is surrounded by lamellar bands of fibrosis with collagen-rich fibers, the perfusion pattern is consistent with the previously known appearance of HCC in CE-US.

Item Type: Article
Uncontrolled Keywords: LIVER-LESIONS; MULTICENTER; DIAGNOSIS; CEUS; Contrast-Enhanced Ultrasound; Fibrolamellar Hepatocellular Carcinoma; Liver
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 May 2024 12:40
Last Modified: 15 May 2024 04:22
URI: https://pred.uni-regensburg.de/id/eprint/59876

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