Schleder, Stephan and May, Matthias and Scholz, Carsten and Dinkel, Johannes and Strotzer, Quirin and Einspieler, Ingo and Dollinger, Marco and Schreyer, Andreas G. and Grassinger, Jochen and Schicho, Andreas (2023) Diagnostic Value of Diffusion-Weighted Imaging with Background Body Signal Suppression (DWIBS) for the Pre-Therapeutic Loco-Regional Staging of Cervical Cancer: A Feasibility and Interobserver Reliability Study. CURRENT ONCOLOGY, 30 (1). pp. 1164-1173. ISSN 1198-0052, 1718-7729
Full text not available from this repository. (Request a copy)Abstract
(1) Background: cervical cancer is one of the leading causes of cancer-related deaths and the fourth most common cancer among women worldwide. Magnetic resonance imaging (MRI) is the modality of choice for loco-regional staging of cervical cancer in the primary diagnostic workup beginning with at least stage IB. (2) Methods: we retrospectively analyzed 16 patients with histopathological proven cervical cancer (FIGO IB1-IVA) for the diagnostic accuracy of standard MRI and standard MRI with diffusion-weighted imaging with background body signal suppression (DWIBS) for the correct pre-therapeutic assessment of the definite FIGO category. (3) Results: In 7 out of 32 readings (22%), DWIBS improved diagnostic accuracy. With DWIBS, four (13%) additional readings were assigned the correct major (I-IV) FIGO stages pre-therapeutically. Interobserver reliability of DWIBS was weakest for parametrial infiltration (k = 0.43; CI-95% 0.00-1.00) and perfect for tumor size <2 cm, infiltration of the vaginal lower third, infiltration of adjacent organs and loco-regional nodal metastases (k = 1.000; CI-95% 1.00-1.00). (4) Conclusions: the pre-therapeutic staging of cervical cancer has a high diagnostic accuracy and interobserver reliability when using standard MRI but can be further optimized with the addition of DWIBS sequences when reporting is performed by an experienced radiologist.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PARAMETRIAL INVOLVEMENT; TUMOR SIZE; CARCINOMA; METAANALYSIS; SURVIVAL; MRI; DWIBS; cervical cancer; staging |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Mar 2024 15:49 |
| Last Modified: | 13 Mar 2024 15:49 |
| URI: | https://pred.uni-regensburg.de/id/eprint/60038 |
Actions (login required)
 |
View Item |
