Salt sensitivity includes effects on immune cell signalling and metabolism

Mueller, Dominik N. and Geisberger, Sabrina and Kleinewietfeld, Markus and Jantsch, Jonathan (2023) Salt sensitivity includes effects on immune cell signalling and metabolism. NATURE REVIEWS IMMUNOLOGY, 23 (6). pp. 341-342. ISSN 1474-1733, 1474-1741

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Abstract

Excess salt (sodium chloride) intake is a risk factor for hypertension and is attributed to increasing rates of morbidity and mortality from cardiovascular diseases. Salt sensitivity is classically defined as the blood pressure response to dietary salt changes. However, in addition to the pivotal role of sodium (Na+) in regulating the osmotic composition of body fluids, we recently reported that Na+ regulates the energy metabolism of immune cells. Thus, we suggest broadening the definition of salt sensitivity to include these effects on cellular immunometabolism.

Item Type: Article
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Apr 2024 10:04
Last Modified: 24 Apr 2024 10:04
URI: https://pred.uni-regensburg.de/id/eprint/60048

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