Beyer, L. P. and Pregler, B. and Verloh, N. and Bruenn, K. and Haimerl, M. and Stroszczynski, C. and Jung, E. M. and Wiggermann, P. (2017) Effect of irreversible electroporation of prostate cancer on microcirculation: Imaging findings in contrast-enhanced T1-weighted 3D MRI. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 67 (3-4). pp. 399-405. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
OBJECTIVES: Irreversible electroporation (IRE) is a novel focal ablation technique applicable for treatment of prostate cancer (PCa). We aim to evaluate imaging findings of T1-weighted contrast-enhanced MRI after percutaneous IRE of low-risk PCa. METHODS: Atotal of 13 male patients underwent IRE of focal low-risk PCa and were included in this analysis. Prostate IRE was conducted using 2-4 electrodes being placed under CT-fluoroscopy guidance. Dynamic contrast-enhanced 3D isotropic fat-saturated T1-weighted MRI (DCE-MRI) was performed 24-72 hours before and 24-72 hours after ablation. RESULTS: Ablated prostate was either homogeneously (8/13 [62%]) or heterogeneously (/13 [38%]) hypo attenuating. Peripheral contrast enhancement manifesting as a hyper attenuating margin was observed during the arterial (60 sec) (3/13 [23%]) and venous (240 sec) (10/13 [77%]) phase. The ablation defect showed a sharp (8/13 [62%]) or blurry (/13 [38%]) margin. CONCLUSIONS: The results showa venous peripheral rim enhancement in most of the cases, indicating reactive hyperaemia. The heterogeneous appearance of the defect zone in some cases may be secondary to sustained vascularization.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ULTRASOUND CEUS FINDINGS; HEPATOCELLULAR-CARCINOMA; ABLATION; IRE; MRI; irreversible electroporation (IRE); prostate cancer; imaging findings |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:01 |
| Last Modified: | 26 Apr 2019 12:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/601 |
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