Magnetic Resonance Imaging of the Sacroiliac Joints in Patients with Suspected Spondyloarthritis - Comparison of Turbo Spin-Echo and Gradient-Echo Sequences for the Detection of Structural Alterations

Dornia, C. and Fleck, M. and Hartung, W. and Niessen, C. and Stroszczynski, C. and Hoffstetter, P. (2015) Magnetic Resonance Imaging of the Sacroiliac Joints in Patients with Suspected Spondyloarthritis - Comparison of Turbo Spin-Echo and Gradient-Echo Sequences for the Detection of Structural Alterations. ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 187 (2). pp. 109-114. ISSN 1438-9029, 1438-9010

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Abstract

Purpose: Magnetic resonance imaging (MRI) is the method of choice for the evaluation of spondyloarthritis (SpA). According to the guidelines of the Assessment of Spondyloarthritis International Society (ASAS) and Outcome Measures in Rheumatology (OMERACT), MRI findings in SpA of the spine and the sacroiliac joints (SIJ) are classified as inflammatory and structural alterations. Modern gradient-echo sequences (GRE) are recommended for optimized detection of structural alterations of the SIJ. We assess the benefit of GRE in the detection of structural alterations of the SIJ in comparison to conventional turbo spin-echo sequences (TSE). Material and Methods: Retrospective study of 114 patients who received MRI of the SIJ for the evaluation of SpA. Structural alterations of the SIJ were assessed by two blinded readers separately for T1 TSE and T2* GRE. The findings were classified according to a previously published chronicity score separately for both sides and sequences. Interobserver reliability was calculated with Cohen's Kappa, and the significance of findings was assessed with the Wilcoxon test. P-values < 0.05 were required for statistical significance. Results: 68 of 114 (60 %) patients showed SpA-typical findings of the SIJ. The average chronicity score for GRE (score 3.3) was significantly higher than for TSE (score 2.6), p = 0.001. The Kappa-values for the interobserver reliability were 0.86-0.90 without any statistically significant differences between both sides and sequences. Conclusion: Both T1 TSE and T2* GRE showed a high interobserver reliability in the detection of structural alterations in patients with SpA. However, T2* GRE detected significantly more structural alterations than T1 TSE and should be an integral part of a modern MRI protocol for the diagnosticworkup of patients with suspected SpA.

Item Type: Article
Uncontrolled Keywords: AXIAL SPONDYLOARTHRITIS; GADOLINIUM; ANATOMY; LESIONS; spondyloarthritis (SpA); sacroiliac joints (SIJ); magnetic resonance imaging (MRI)
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 25 Jul 2019 07:05
Last Modified: 25 Jul 2019 07:05
URI: https://pred.uni-regensburg.de/id/eprint/6015

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