Delivery of antibacterial agents for wound healing applications using polysaccharide-based scaffolds

Nosrati, Hamed and Heydari, Morteza and Tootiaei, Zahra and Ganjbar, Saeid and Khodaei, Mohammad (2023) Delivery of antibacterial agents for wound healing applications using polysaccharide-based scaffolds. ELSEVIER, AMSTERDAM.

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Abstract

Skin is the first line of defense against pathogenic microorganisms. Any serious damage to this organ can lead to bacterial invasion and wound infection. Such infections can cause not only a delay in the healing process, but also more serious complications such as tissue necrosis or even sepsis, which can lead to life-threatening con-ditions. Therefore, wound management is a clinically critical issue. In this regard, scaffolds containing anti-bacterial nanobiomaterials or other agents have emerged as effective methods for reducing wound bacterial colonization and infection, thus enhancing wound healing. Because of their immunological safety, biodegrad-ability and non-toxicity, polysaccharide-based scaffolds have piqued the interest of researchers for the delivery of antibacterial agents and nanobiomaterials for wound healing applications. This review focuses on antibacterial nanobiomaterials and agents, as well as their delivery via polysaccharide-based scaffolds for wound healing applications.

Item Type: Other
Uncontrolled Keywords: SOFT-TISSUE INFECTIONS; LINKED CHITOSAN HYDROGELS; HYALURONIC-ACID; CROSS-LINKING; SILVER NANOPARTICLES; ANTIMICROBIAL ACTIVITY; IN-VITRO; BACTERIAL CELLULOSE; CHONDROITIN SULFATE; ALGINATE HYDROGELS; Antibacterial properties; Polysaccharides; Scaffolds; Wound healing
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Immunologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 30 Jan 2024 14:43
Last Modified: 30 Jan 2024 14:43
URI: https://pred.uni-regensburg.de/id/eprint/60269

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