von Fritschen, Uwe and Kremer, Thomas and Prantl, Lukas and Fricke, Alba (2023) Breast Implant-Associated Tumors. GEBURTSHILFE UND FRAUENHEILKUNDE, 83 (6). pp. 686-693. ISSN 0016-5751, 1438-8804
Full text not available from this repository. (Request a copy)Abstract
In addition to anaplastic large T-cell lymphomas (BIA-ALCL), other implant-related tumors have been described for some years. Squamous cell carcinoma (SSC) and B-cell lymphomas occurred in very rare cases. The unexplained pathogenesis as well as the unclear individual risk profile is an ongoing source of uncertainty for patients and physicians. The pathogenesis of the tumors is still largely not understood. While BIA-ALCL occurs more frequently with textured breast implants, other tumors were also observed with smooth implants and at other implant sites. Multiple potential mechanisms are discussed. It is suspected that the etiology of a chronic inflammatory response and subsequently immunostimulation is multifactorial and appears to play a key role in the malignant transformation. Since there are currently no sufficiently valid data for a specific risk assessment, this must be done with caution. This article presents the incidence, pathogenesis, as well as the level of evidence according to the current state of knowledge, and evaluates and discusses the current literature.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LARGE-CELL LYMPHOMA; NCCN CONSENSUS GUIDELINES; EPSTEIN-BARR-VIRUS; BIA-ALCL; CARCINOMA; CAPSULE; DIAGNOSIS; RISK; MANAGEMENT; REGISTRY; breast implant; lymphoma; BIA-SCC; immunostimulation; textured implants; squamous cell carcinoma; implant-associated tumors; BIA-ALCL |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Mar 2024 10:28 |
| Last Modified: | 13 Mar 2024 10:28 |
| URI: | https://pred.uni-regensburg.de/id/eprint/60270 |
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