Vega, Kimberly Benedetti and Delgado, Jose Antonio Campos and Pugnal, Lucas V. B. L. and Koenig, Burkhard and Correia, Jose Tiago Menezes and Paixao, Marcio Weber (2023) Divergent Functionalization of Styrenes via Radical/Polar Crossover with CO<sub>2</sub> and Sodium Sulfinates. CHEMISTRY-A EUROPEAN JOURNAL, 29 (19). ISSN 0947-6539, 1521-3765
Full text not available from this repository. (Request a copy)Abstract
Sulfones and carboxylic acids are prominent motifs widely present in the chemical structure of agrochemicals, pharmaceuticals and many other highly valuable compounds. Herein, we describe a conjunctive strategy for the precise installation of these functionalities onto styrenes using sodium sulfinates and CO2 as coupling partners. The protocol allowed the preparation of carboxy-sulfonylated compounds in good yields and broad functional group tolerance. Additionally, taking advantage of the leaving group ability of the sulfone moiety, a one-pot photocatalytic carboxy-sulfonylation-elimination strategy was developed for the synthesis of alpha-aryl-acrylates.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BETA-SELECTIVE HYDROCARBOXYLATION; CARBOXYLIC-ACIDS; POTENT INHIBITORS; EFFICIENT; ALKENES; DICARBOFUNCTIONALIZATION; POLYMERIZATION; SULFONYLATION; CONVERSION; COUPLINGS; alpha-substituted acrylates; carbon dioxide; carboxylic acids; photocatalysis; sustainability |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Mar 2024 10:41 |
| Last Modified: | 19 Mar 2024 10:41 |
| URI: | https://pred.uni-regensburg.de/id/eprint/60348 |
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