Hegyi, Peter and Seidler, Ursula and Kunzelmann, Karl (2023) CFTR-beyond the airways: Recent findings on the role of the CFTR channel in the pancreas, the intestine and the kidneys. JOURNAL OF CYSTIC FIBROSIS, 22. S17-S22. ISSN 1569-1993, 1873-5010
Full text not available from this repository. (Request a copy)Abstract
With increased longevity of patients suffering from cystic fibrosis, and widespread lung transplantation facilities, the sequelae of defective CFTR in other organs than the airways come to the fore. This minireview highlights recent scientific progress in the understanding of CFTR function in the pancreas, the intestine and the kidney, and explores potential therapeutic strategies to combat defective CFTR function in these organs. (C) 2023 The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSMEMBRANE CONDUCTANCE REGULATOR; DUCTAL BICARBONATE SECRETION; CYSTIC-FIBROSIS; METABOLIC ALKALOSIS; RENAL CLEARANCE; HCO3-SECRETION; CL-CHANNELS; MOUSE MODEL; SODIUM; PATHOPHYSIOLOGY; Mucoviscidosis; Pancreas; Pancreatitis; Intestine; NHE3; Tenapanor; DIOS; Bicarbonate secretion; Kidney; Collecting duct; Metabolic alkalosis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Karl Kunzelmann |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 30 Jan 2024 12:22 |
| Last Modified: | 30 Jan 2024 12:22 |
| URI: | https://pred.uni-regensburg.de/id/eprint/60434 |
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