Kauffmann, P. and Troeltzsch, M. and Cordesmeyer, R. and Heidekrueger, P. I. and Schliephake, H. and Canis, M. and Wolff, H. A. and Rave-Fraenk, M. and Stroebel, P. and Kehrer, A. and Prantl, L. and Aung, T. (2017) Presentation of a variation of the chorioallantoic membrane set up as a potential model for individual therapy for squamous cell carcinoma of the oropharynx. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 67 (3-4). pp. 453-457. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
The chorioallantoic membrane of fertilized chicken eggs in an early phase of breeding presents an approved test situation for the growth and treatment of human cancer cells. These models work due to the inoculation of cells into the membrane that stays within the egg shell during the time of investigation. In this study a modification of this model is presented. Samples of native tumors, rather than cell lines, are transplanted into the membrane and the body of the egg is taken out of the shell and placed in a plastic bowl. These modifications lead to an enhanced accessibility to the chorioallantoic membrane and the surrounding vessels thus facilitating intra venous access and application of pharmaceuticals and a focused radiotherapy. With the current modifications the embryo was kept alive and additionally, the vascularized tumor environment was preserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EMBRYO; ANGIOGENESIS; SYSTEM; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:01 |
| Last Modified: | 26 Apr 2019 12:19 |
| URI: | https://pred.uni-regensburg.de/id/eprint/605 |
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