Jantsch, Jonathan and Schoedel, Johannes (2015) Hypoxia and hypoxia-inducible factors in myeloid cell-driven host defense and tissue homeostasis. IMMUNOBIOLOGY, 220 (2). pp. 305-314. ISSN 0171-2985
Full text not available from this repository. (Request a copy)Abstract
The impact of tissue oxygenation and hypoxia on immune cells has been recognized as a major determinant of host defense and tissue homeostasis. In this review, we will summarize the available data on tissue oxygenation in inflamed and infected tissue and the effect of low tissue oxygenation on myeloid cell function. Furthermore, we will highlight effects of the master regulators of the cellular hypoxic response, hypoxia-inducible transcription factors (HIF), in myeloid cells in antimicrobial defense and tissue homeostasis. (C) 2014 Elsevier GmbH. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NITRIC-OXIDE SYNTHASE; INNATE IMMUNE-RESPONSE; OXYGEN-TENSION; HUMAN-NEUTROPHILS; DENDRITIC CELLS; FACTOR 1-ALPHA; IN-VIVO; MYCOBACTERIUM-TUBERCULOSIS; LEISHMANIA-AMAZONENSIS; ACTIVATED MACROPHAGES; Myeloid cells; Hypoxia; Hypoxia-inducible transcription factors |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 Aug 2020 08:32 |
| Last Modified: | 14 Aug 2020 08:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6070 |
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