EFSUMB Technical Review - Update 2023: Dynamic Contrast-Enhanced Ultrasound (DCE-CEUS) for the Quantification of Tumor Perfusion

Dietrich, Christoph F. and Correas, Jean-Michel and Cui, Xin-Wu and Dong, Yi and Havre, Roald Flesland and Jenssen, Christian and Jung, Ernst Michael and Krix, Martin and Lim, Adrian and Lassau, Nathalie and Piscaglia, Fabio (2023) EFSUMB Technical Review - Update 2023: Dynamic Contrast-Enhanced Ultrasound (DCE-CEUS) for the Quantification of Tumor Perfusion. GEORG THIEME VERLAG KG, STUTTGART.

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Abstract

Dynamic contrast-enhanced ultrasound (DCE-US) is a technique to quantify tissue perfusion based on phase-specific enhancement after the injection of microbubble contrast agents for diagnostic ultrasound. The guidelines of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) published in 2004 and updated in 2008, 2011, and 2020 focused on the use of contrast-enhanced ultrasound (CEUS), including essential technical requirements, training, investigational procedures and steps, guidance regarding image interpretation, established and recommended clinical indications, and safety considerations. However, the quantification of phase-specific enhancement patterns acquired with ultrasound contrast agents (UCAs) is not discussed here. The purpose of this EFSUMB Technical Review is to further establish a basis for the standardization of DCE-US focusing on treatment monitoring in oncology. It provides some recommendations and descriptions as to how to quantify dynamic ultrasound contrast enhancement, and technical explanations for the analysis of time-intensity curves (TICs). This update of the 2012 EFSUMB introduction to DCE-US includes clinical aspects for data collection, analysis, and interpretation that have emerged from recent studies. The current study not only aims to support future work in this research field but also to facilitate a transition to clinical routine use of DCE-US.

Item Type: Other
Uncontrolled Keywords: CLINICAL-PRACTICE RECOMMENDATIONS; RENAL MICROVASCULAR PERFUSION; CARCINOMA EARLY EVALUATION; LOW MECHANICAL INDEX; CROHNS-DISEASE; REPLENISHMENT KINETICS; ENDOSCOPIC ULTRASOUND; TREATMENT RESPONSE; MULTIVESSEL MODEL; TARGETED THERAPY; contrast-enhanced ultrasound; guidelines; quantification; therapy monitoring; tumor perfusion
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 May 2024 06:06
Last Modified: 07 May 2024 06:06
URI: https://pred.uni-regensburg.de/id/eprint/60848

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