Mohty, Mohamad and Malard, Florent and Alaskar, Ahmed S. and Aljurf, Mahmoud and Arat, Mutlu and Bader, Peter and Baron, Frederic and Bazarbachi, Ali and Blaise, Didier and Brissot, Eolia and Ciceri, Fabio and Corbacioglu, Selim and Dalle, Jean-Hugues and Dignan, Fiona and Huynh, Anne and Kenyon, Michelle and Nagler, Arnon and Pagliuca, Antonio and Peric, Zinaida and Richardson, Paul G. and Ruggeri, Annalisa and Ruutu, Tapani and Yakoub-Agha, Ibrahim and Duarte, Rafael F. and Carreras, Enric (2023) Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a refined classification from the European society for blood and marrow transplantation (EBMT). BONE MARROW TRANSPLANTATION, 58 (7). pp. 749-754. ISSN 0268-3369, 1476-5365
Full text not available from this repository. (Request a copy)Abstract
Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation (HCT). A new definition for diagnosis, and a severity grading system for SOS/VOD in adult patients, was reported a few years ago on behalf of the European Society for Blood and Marrow Transplantation (EBMT). The aim of this work is to update knowledge regarding diagnosis and severity assessment of SOS/VOD in adult patients, and also its pathophysiology and treatment. In particular, we now propose to refine the previous classification and distinguish probable, clinical and proven SOS/VOD at diagnosis. We also provide an accurate definition of multiorgan dysfunction (MOD) for SOS/VOD severity grading based on Sequential Organ Failure Assessment (SOFA) score.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEPATIC VENOOCCLUSIVE DISEASE; STEM-CELL TRANSPLANTATION; ORGAN FAILURE; LIVER; COMPLICATIONS; SEPSIS; COHORT |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Mar 2024 08:47 |
| Last Modified: | 13 Mar 2024 08:47 |
| URI: | https://pred.uni-regensburg.de/id/eprint/60889 |
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