Emons, Gunter and Steiner, Eric and Vordermark, Dirk and Uleer, Christoph and Paradies, Kerstin and Tempfer, Clemens and Aretz, Stefan and Cremer, Wolfgang and Hanf, Volker and Mallmann, Peter and Ortmann, Olaf and Roemer, Thomas and Schmutzler, Rita K. and Horn, Lars-Christian and Kommoss, Stefan and Lax, Sigurd and Schmoeckel, Elisa and Mokry, Theresa and Grab, Dieter and Reinhardt, Michael and Steinke-Lange, Verena and Brucker, Sara Y. and Kiesel, Ludwig and Witteler, Ralf and Fleisch, Markus C. and Proempeler, Heinrich and Friedrich, Michael and Hoecht, Stefan and Lichtenegger, Werner and Mueller, Michael and Runnebaum, Ingo and Feyer, Petra and Hagen, Volker and Juhasz-Boess, Ingolf and Letsch, Anne and Niehoff, Peter and Zeimet, Alain Gustave and Battista, Marco Johannes and Petru, Edgar and Widhalm, Simone and van Oorschot, Birgitt and Panke, Joan Elisabeth and Weis, Joachim and Dauelsberg, Timm and Haase, Heidemarie and Beckmann, Matthias W. and Jud, Sebastian and Wight, Edward and Prott, Franz-Josef and Micke, Oliver and Bader, Werner and Reents, Nicola and Henscher, Ulla and Tholen, Reina and Schallenberg, Miriam and Rahner, Nils and Mayr, Doris and Kreissl, Michael and Lindel, Katja and Mustea, Alexander and Strnad, Vratislav and Goerling, Ute and Bauerschmitz, Gerd J. and Langrehr, Jan and Neulen, Joseph and Ulrich, Uwe Andreas and Nothacker, Monika J. and Bloedt, Susanne and Follmann, Markus and Langer, Thomas and Wenzel, Gregor and Weber, Sylvia and Erdogan, Saskia (2023) Endometrial Cancer. Guideline of the DGGG, DKG and DKH (S3-Level, AWMF Registry Number 032/034-OL, September 2022). Part 1 with Recommendations on the Epidemiology, Screening, Diagnosis and Hereditary Factors of Endometrial Cancer, Geriatric Assessment and Supply Structures. GEBURTSHILFE UND FRAUENHEILKUNDE, 83 (08). pp. 919-961. ISSN 0016-5751, 1438-8804
Full text not available from this repository. (Request a copy)Abstract
The S3-guideline on endometrial cancer, first published in April 2018, was reviewed in its entirety between April 2020 and January 2022 and updated. The review was carried out at the request of German Cancer Aid as part of the Oncology Guidelines Program and the lead coordinators were the German Society for Gynecology and Obstetrics (DGGG), the Gynecology Oncology Working Group (AGO) of the German Cancer Society (DKG) and the German Cancer Aid (DKH). The guideline update was based on a systematic search and assessment of the literature published between 2016 and 2020. All statements, recommendations and background texts were reviewed and either confirmed or amended. New statements and recommendations were included where necessary. Aim The use of evidence-based risk-adapted therapies to treat women with endometrial cancer of low risk prevents unnecessarily radical surgery and avoids non-beneficial adjuvant radiation therapy and/or chemotherapy. For women with endometrial cancer and a high risk of recurrence, the guideline defines the optimum level of radical surgery and indicates whether chemotherapy and/or adjuvant radiation therapy is necessary. This should improve the survival rates and quality of life of these patients. The S3- guideline on endometrial cancer and the quality indicators based on the guideline aim to provide the basis for the work of certified gynecological cancer centers. Methods The guideline was first compiled in 2018 in accordance with the requirements for S3-level guidelines and was updated in 2022. The update included an adaptation of the source guidelines identified using the German Instrument for Methodological Guideline Appraisal (DELBI). The update also used evidence reviews which were created based on selected literature obtained from systematic searches in selected literature databases using the PICO process. The Clinical Guidelines Service Group was tasked with carrying out a systematic search and assessment of the literature. Their results were used by interdisciplinary working groups as a basis for developing suggestions for recommendations and statements which were then modified during structured online consensus conferences and/or additionally amended online using the DELPHI process to achieve a consensus. Recommendations Part 1 of this short version of the guideline provides recommendations on epidemiology, screening, diagnosis, and hereditary factors. The epidemiology of endometrial cancer and the risk factors for developing endometrial cancer are presented. The options for screening and themethods used to diagnose endometrial cancer are outlined. Recommendations are given for the prevention, diagnosis, and therapy of hereditary forms of endometrial cancer. The use of geriatric assessment is considered and existing structures of care are presented.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HORMONE-REPLACEMENT THERAPY; POLYCYSTIC-OVARY-SYNDROME; PREEXISTING DIABETES-MELLITUS; BODY-MASS INDEX; LYNCH-SYNDROME; PHYSICAL-ACTIVITY; BREAST-CANCER; GLYCEMIC INDEX; LONG-TERM; POSTMENOPAUSAL WOMEN; endometrial cancer; epidemiology; hereditary factors; geriatric assessment; supply structures |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde) Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Geburtshilfe) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 30 Jan 2024 06:56 |
| Last Modified: | 30 Jan 2024 06:56 |
| URI: | https://pred.uni-regensburg.de/id/eprint/60974 |
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