Investigation of an efficient multi-modal convolutional neural network for multiple sclerosis lesion detection

Raab, Florian and Malloni, Wilhelm and Wein, Simon and Greenlee, Mark W. and Lang, Elmar W. (2023) Investigation of an efficient multi-modal convolutional neural network for multiple sclerosis lesion detection. SCIENTIFIC REPORTS, 13 (1): 21154. ISSN 2045-2322,

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Abstract

In this study, an automated 2D machine learning approach for fast and precise segmentation of MS lesions from multi-modal magnetic resonance images (mmMRI) is presented. The method is based on an U-Net like convolutional neural network (CNN) for automated 2D slice-based-segmentation of brain MRI volumes. The individual modalities are encoded in separate downsampling branches without weight sharing, to leverage the specific features. Skip connections input feature maps to multi-scale feature fusion (MSFF) blocks at every decoder stage of the network. Those are followed by multi-scale feature upsampling (MSFU) blocks which use the information about lesion shape and location. The CNN is evaluated on two publicly available datasets: The ISBI 2015 longitudinal MS lesion segmentation challenge dataset containing 19 subjects and the MICCAI 2016 MSSEG challenge dataset containing 15 subjects from various scanners. The proposed multi-input 2D architecture is among the top performing approaches in the ISBI challenge, to which open-access papers are available, is able to outperform state-of-the-art 3D approaches without additional post-processing, can be adapted to other scanners quickly, is robust against scanner variability and can be deployed for inference even on a standard laptop without a dedicated GPU.

Item Type: Article
Uncontrolled Keywords: SEGMENTATION;
Subjects: 000 Computer science, information & general works > 004 Computer science
100 Philosophy & psychology > 150 Psychology
Divisions: Human Sciences > Institut für Psychologie > Lehrstuhl für Psychologie I (Allgemeine Psychologie I und Methodenlehre) - Prof. Dr. Mark W. Greenlee
Informatics and Data Science
Depositing User: Dr. Gernot Deinzer
Date Deposited: 19 Apr 2024 14:01
Last Modified: 19 Apr 2024 14:01
URI: https://pred.uni-regensburg.de/id/eprint/61204

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