Schotola, Hanna and Kirsch, Karl-Christian and Hoecker, Jan and Egan, Michael and Buettner, Benedikt and Wiese, Christoph and Mansur, Ashham and Hinz, Jose Maria and Bergmann, Ingo (2015) Ketamine in outpatient arthroscopic shoulder surgery: Effects on postoperative pain, hemodynamic stability and process times. OPEN MEDICINE, 10 (1). pp. 297-305. ISSN 2391-5463,
Full text not available from this repository. (Request a copy)Abstract
Background: Pain after arthroscopic shoulder surgery is often severe, and establishing a pain treatment regimen that does not delay discharge can be challenging. The reported ability of ketamine to prevent opioid-induced hyperalgesia has not been investigated in this particular setting. Methods: 300 adult patients scheduled for shoulder arthroscopy under general anesthesia were recruited for this observational clinical trial and were allotted to either receive 1mg/kg IV bolus of ketamine before surgery (ketamine group, KG) or to a control group (CG) without ketamine. NRS pain scores were obtained on the operative day and on postoperative days 1 and 2 and compared between groups. Secondary variables were blood pressure, heart rate, process times, satisfaction with the anesthetic and unwanted effects. Results: Pain severity did not differ significantly between the groups at any time. Propofol injection rate and cumulative dose were higher in the KG. Heart rates and blood pressures were similar. Time to emergence and time in PACU were longer and vomiting was more frequent in patients given ketamine. Conclusion: Preoperative low-dose ketamine added to a general anesthetic does not reduce perioperative pain after outpatient shoulder arthroscopy. It increases procedural times and the incidence of PONV.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | OPIOID-INDUCED HYPERALGESIA; DOSE KETAMINE; ANESTHESIA; REMIFENTANIL; ANALGESIA; PROPOFOL; POSITION; HUMANS; Ketamine; outpatient; day surgery; postoperative pain; general anaesthesia |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 25 Jul 2019 13:04 |
| Last Modified: | 25 Jul 2019 13:04 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6129 |
Actions (login required)
 |
View Item |
