Niessen, C. and Jung, E. M. and Beyer, L. and Pregler, B. and Dollinger, M. and Haimerl, M. and Scheer, F. and Stroszczynski, C. and Wiggermann, P. (2015) Percutaneous irreversible electroporation (IRE) of prostate cancer: Contrast-enhanced ultrasound (CEUS) findings. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 61 (2). pp. 135-141. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
PURPOSE: To evaluate the use of contrast-enhanced ultrasound (CEUS) after irreversible electroporation (IRE) of prostatic cancer tissue to assess the ablation status by depicting microvascularisation in the ablation area. MATERIALS AND METHODS: Retrospective evaluation of CEUS of 13 patients (mean age: 61.4 +/- 7.5 years) with histologically confirmed prostatic cancer who underwent percutaneous IRE. In the course of clinical routine, the tumor lesions were documented before, immediately after, and 1 day after the ablation using color-coded transabdominal and transrectal CEUS. The obtained image data (DICOM loops and images) were subsequently evaluated by 2 experienced radiologists and assessed with regard to micro vascularisation by means of a 5-point scale. RESULTS: CEUS images showed significantly reduced microcirculation of the lesions (mean 0.9 +/- 0.6 cm (0.5-1.5 cm) after IRE. Microcirculation was reduced from 2.15 +/- 0.56 prior to ablation to 0.65 +/- 0.63 (p < 0.001) immediately after the ablation and to 0.27 +/- 0.44 one day after IRE (p < 0.001). CONCLUSION: This study showed rapid and significant reduction of the microcirculation in the ablation area after percutaneous IRE of prostatic cancer tissue.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MANAGEMENT; MICROVASCULARIZATION; THERAPY; Irreversible electroporation; prostate cancer; percutaneous ablation; contrast-enhanced ultrasound |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Jul 2019 10:22 |
| Last Modified: | 26 Jul 2019 10:22 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6165 |
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