Pschierer, K. and Grothues, D. and Rennert, J. and da Silva, N. Platz Batista and Schreyer, A. G. and Melter, M. and Stroszczysnski, C. and Jung, E. M. (2015) Evaluation of the diagnostic accuracy of CEUS in children with benign and malignant liver lesions and portal vein anomalies. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 61 (2). pp. 333-345. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
OBJECTIVE: Comparison of the diagnostic findings of MRI, CT and CEUS in children with benign and malignant and portal venous anomalies of the liver. MATERIALS/METHODS: Retrospective analysis of the diagnostic findings of CEUS, MRI and CT scans in 56 children (age 0-17 years) with a total of 60 benign and malignant liver lesions and anomalies of the portal vein/perfusion. All patients underwent CEUS using sulphur hexafluoride microbubbles and a multi-frequency probe (1-5 MHz, 6-9 MHz). Cine-loops were stored up to 3 minutes. MRI was performed in 38 lesions. CT was performed in 8 lesions. RESULTS: Out of the 56 patients 49 liver lesions (48 benign, 1 malignant), 9 anomalies of the portal vein/perfusion and 2 of the biliary system were detected. 16/49 lesions were analyzed histopathologically. Using CEUS, the characterization of the lesions was possible in 45 out of 49 cases. In 32 cases, CEUS provided the exact diagnosis. Only two benign lesions were falsely categorized as malignant. Findings of MRI and CEUS were concordant in 84% of cases (n = 32/38). CEUS considered 1 benign lesion to be malignant. 2 lesions were not detectable and in 3 lesions no definite diagnosis was established using MRI. Findings of CT and CEUS were concordant in 5 of 8 cases. In 21 lesions CEUS as the only imaging modality was found to be sufficient for diagnostics. CONCLUSION: Despite the restricted indications for using CEUS in children, it offers a high diagnostic detection rate (93%) for characterization of liver lesions and portal vein anomalies.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CONTRAST-ENHANCED ULTRASOUND; FOCAL NODULAR HYPERPLASIA; DEGUM MULTICENTER TRIAL; CLINICAL-PRACTICE; COMPUTED-TOMOGRAPHY; HEPATOCELLULAR-CARCINOMA; SAFETY; TUMORS; ULTRASONOGRAPHY; COOPERATION; Contrast enhanced ultrasound (CEUS); children; liver; diagnostic value; safety |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Jul 2019 10:28 |
| Last Modified: | 26 Jul 2019 10:28 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6168 |
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