Poznik, Michal and Maitra, Uday and Koenig, Burkhard (2015) The interface makes a difference: lanthanide ion coated vesicles hydrolyze phosphodiesters. ORGANIC & BIOMOLECULAR CHEMISTRY, 13 (38). pp. 9789-9792. ISSN 1477-0520, 1477-0539
Full text not available from this repository. (Request a copy)Abstract
Lanthanide ions are strong Lewis acids. Their complexation to a variety of ligands can further enhance their Lewis acidity allowing the hydrolysis of phosphoesters and even DNA. We show that the interaction of lanthanide ions with vesicles from zwitterionic phosphatidylcholine lipids gives supramolecular structures in which the metal ion is loosely coordinated to the surface. This assembly provides a high density of Lewis-acidic metal centres, which hydrolyze phosphodiesters with enhanced rates.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MICELLAR-SOLUTIONS; DNA; COMPLEXES; NUCLEASES; MEMBRANE; CLEAVAGE; BINDING; ATTACK; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Jul 2019 08:59 |
| Last Modified: | 29 Jul 2019 08:59 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6195 |
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