Verburg, Maurice and Lang, Martin and Muehlstaedt, Michael and Klein, Annette and Schauber, Juergen and Sattler, Elke C. and Kunte, Christian (2015) Cutaneous Squamous Cell Carcinoma with Perineural Invasion: Report on Eight Cases and Review of the Literature. DERMATOLOGY, 230 (2). pp. 135-142. ISSN 1018-8665, 1421-9832
Full text not available from this repository. (Request a copy)Abstract
Background: Perineural invasion (PNI) in cutaneous squamous cell carcinoma (SCC) is considered to be a negative prognostic factor. A lot of uncertainty remains regarding the classification, diagnosis, treatment and prognosis of SCC with PNI. Objective: To describe typical courses of SCC with PNI and associated findings in order to suggest an optimized diagnostic and therapeutic approach. Methods: We present eight cases of SCC with PNI, considering patient and tumor characteristics, histology, treatment and clinical course regarding local recurrence and metastasization. Results: SCC patients with PNI have a higher rate of local recurrences and greater risk for metastasization than SCC patients without PNI. Age ranged from 68 to 77 years, 6 patients were male and 2 female, with all tumors localized on the head. Three patients had chronic lymphocytic leukemia. Conclusion: Based on the data of this series and the current literature, we make suggestions for better diagnostic and therapeutic management. (C) 2014 S. Karger AG, Basel
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MOHS MICROGRAPHIC SURGERY; NECK; HEAD; SKIN; MALIGNANCIES; MANAGEMENT; OUTCOMES; BASAL; Squamous cell carcinoma; Perineural invasion; Radiotherapy; Mohs surgery; Skip lesions |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 13 Aug 2020 15:25 |
| Last Modified: | 13 Aug 2020 15:25 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6285 |
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