Ionescu, Andrei and Brambilla, Eugenio and Wastl, Daniel S. and Giessibl, Franz J. and Cazzaniga, Gloria and Schneider-Feyrer, Sibylle and Hahnel, Sebastian (2015) Influence of matrix and filler fraction on biofilm formation on the surface of experimental resin-based composites. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 26 (1): 58. ISSN 0957-4530, 1573-4838
Full text not available from this repository. (Request a copy)Abstract
The aim of this study was to investigate the impact of resin matrix chemistry and filler fraction on biofilm formation on the surface of experimental resin-based composites (RBCs). Specimens were prepared from eight experimental RBC formulations differing in resin matrix blend (BisGMA/TEGDMA in a 7:3 wt% ratio or UDMA/aliphatic dimethacrylate in a 1:1 wt% ratio) and filler fraction (no fillers; 65 wt% dental glass with an average diameter of 7 or 0.7 mu m or 65 wt% SiO2 with an average diameter of 20 nm). Surface roughness, surface free energy, and chemical surface composition were determined; surface topography was visualized using atomic force microscopy. Biofilm formation was simulated under continuous flow conditions for a 48 h period using a monospecies Streptococcus mutans and a multispecies biofilm model. In the monospecies biofilm model, the impact of the filler fraction overruled the influence of the resin matrix, indicating lowest biofilm formation on RBCs with nano-scaled filler particles and those manufactured from the neat resin blends. The multispecies model suggested a more pronounced effect of the resin matrix blend, as significantly higher biofilm formation was identified on RBCs with a UDMA/dimethacrylate matrix blend than on those including a BisGMA/TEGDMA matrix blend but analogous filler fractions. Although significant differences in surface properties between the various materials were identified, correlations between the surface properties and biofilm formation were poor, which highlights the relevance of surface topography and chemistry. These results may help to tailor novel RBC formulations which feature reduced biofilm formation on their surface.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | STREPTOCOCCUS-MUTANS; RESTORATIVE MATERIALS; CARIES FORMATION; PLAQUE; RELEASE; COMMUNITIES; LONGEVITY; ROUGHNESS; PROTEINS; POLYMERS; |
| Subjects: | 500 Science > 530 Physics 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Zahnärztliche Prothetik Physics > Institute of Experimental and Applied Physics > Chair Professor Giessibl > Group Franz J. Giessibl |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Aug 2019 08:48 |
| Last Modified: | 02 Aug 2019 08:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6312 |
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