Aziz, Atiqullah and Madersbacher, Stephan and Ott, Wolfgang and Mayr, Roman and Comploj, Evi and Pycha, Armin and Denzinger, Stefan and Fritsche, Hans-Martin and Burger, Maximilian and Gierth, Michael (2015) Comparative Analysis of Gender-Related Differences in Symptoms and Referral Patterns prior to Initial Diagnosis of Urothelial Carcinoma of the Bladder: A Prospective Cohort Study. UROLOGIA INTERNATIONALIS, 94 (1). pp. 37-44. ISSN 0042-1138, 1423-0399
Full text not available from this repository. (Request a copy)Abstract
Objective: To analyze gender-specific differences regarding clinical symptoms, referral patterns and tumor biology prior to initial diagnosis of urothelial carcinoma of the bladder (UCB). Methods: A consecutive series of patients with an initial diagnosis of UCB was included. All patients completed a questionnaire on demographics, clinical symptoms and referral patterns. Results: In total, 68 patients (50 men, 18 women) with newly diagnosed UCB at admission for transurethral resection of bladder tumors were recruited. Dysuria was more often observed in women (55.6 vs. 38.0%, p = 0.001). Direct consultation of the urologist was conducted by 84.0% of males and 66.7% of females (p = 0.120). One third of the women saw their general practitioner and/or gynecologist once or twice (p = 0.120) before referral to the urologist. Furthermore, women were significantly more often treated for urinary tract infections than men (61.1 vs. 20.0%, p = 0.005). Cystoscopy at first presentation to the urologist was more often performed in men than women (88.0 vs. 66.7%, p = 0.068), with a more favorable tumor detection rate at first cystoscopy in men (96.0 vs. 50.0%, p < 0.001). Conclusions: Delayed referral patterns might lead to deferred diagnosis of UCB and consequently to adverse outcome. Thus, primary care physicians might consider referring patients with bladder complaints to specialized care earlier. (C) 2014 S. Karger AG, Basel
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSITIONAL-CELL CARCINOMA; CANCER-SPECIFIC SURVIVAL; RADICAL CYSTECTOMY; URINARY-TRACT; FEMALE GENDER; RISK; HEMATURIA; RECURRENCE; PROGRESSION; MORTALITY; Urinary bladder neoplasms; Carcinoma; Transitional cell; Sex characteristics; Referrals |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Aug 2019 09:33 |
| Last Modified: | 02 Aug 2019 09:33 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6317 |
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