COVID-19 infection triggered idiopathic capillary leak syndrome treated with ECMELLA

Wester, Michael and Drasch, Thomas and Schneckenpointner, Roland and Foltan, Maik and Philipp, Alois and Mueller, Thomas and Banas, Bernhard and Maier, Lars S. and Lubnow, P. D. Matthias (2024) COVID-19 infection triggered idiopathic capillary leak syndrome treated with ECMELLA. HELIYON, 10 (14): e34693. ISSN , 2405-8440

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Abstract

Background: Idiopathic systemic capillary leak syndrome (ISCLS) is characterized by recurrent systemic capillary leakage and hypovolemic shock. Case presentation: We report a 59-year-old Caucasian man with ISCLS and persistent hypovolemic and cardiogenic shock after COVID-19 infection. Mechanical circulatory support was provided with veno-arterial extracorporeal membrane oxygenation and a microaxial pump. Massive fluid resuscitation was needed. Subsequent complications prolonged the intensive care treatment. Mechanical circulatory support was needed for 22 days. Cardiac function eventually fully recovered, and the patient survived without neurologic compromise. Conclusions: This case of severe ISCLS triggered by COVID-19 highlights that even the most severe hypovolemic and cardiogenic shock may be reversible in ISCLS.

Item Type: Article
Uncontrolled Keywords: ; Case report; VA-ECMO; Impella; COVID19; ISCLS
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Jul 2025 09:17
Last Modified: 15 Jul 2025 09:17
URI: https://pred.uni-regensburg.de/id/eprint/63445

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