Oppolzer, Immanuel A. and Schnabel, Marco J. and Hammer, Selma and Zilles, Hannah and Haas, Maximilian and Gossler, Christopher and Mueller, Maximilian Reinhard and Burger, Maximilian and Gierth, Michael (2025) Impact of SARS-CoV-2 Pandemic on Diagnosis of Prostate Cancer. UROLOGIA INTERNATIONALIS, 109 (2). pp. 158-166. ISSN 0042-1138, 1423-0399
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Introduction: The aim of this study was to prove if the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic resulted in a delay in diagnosis and treatment of prostate cancer (PC). Methods: A monocentric, retrospective analysis was conducted at a university cancer center. Included were all patients with untreated PC diagnosed between January 2019 and December 2021. The observation covered 22 months of the SARS-CoV-2 pandemic and 14 months preceding it. Results: Nine hundred sixty-nine men prior (T0) and 1,343 during the pandemic (T1) were included. Mean age was 68.0 (SD 8.2). Median initial prostate-specific antigen was 8.1 ng/mL (T0) and 7.9 ng/mL (T1, p = 0.288). Time from biopsy to tumor board (T0: 1.3 months vs. T1: 0.9 months, p = 0.001), to staging (T0: 1.1 months vs. T1: 0.75 months, p = 0.707), and to therapy (T0: 3.0 months vs. T1: 2.0 months, p < 0.001) was shortened during the pandemic. Classified by d'Amico, a significant shift toward higher risk groups was seen (p = 0.024). Local staging showed an insignificant increase in locally advanced PCs. Metastatic diseases decreased from 10.3% to 8.9% (p = 0.433). Pathological staging showed pT3+ in 44.4% versus 44.7% (p = 0.565) and pN+ in 9.9% versus 9.6% (p = 0.899). Conclusion: Regarding the diagnosis and treatment of PC, we could not demonstrate any delays due to the SARS-CoV-2 pandemic.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | COVID-19; OUTCOMES; Prostate cancer; Delay in diagnosis; Severe acute respiratory syndrome coronavirus 2; COVID-19; Clinical data |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 03 Mar 2026 10:15 |
| Last Modified: | 03 Mar 2026 10:15 |
| URI: | https://pred.uni-regensburg.de/id/eprint/63686 |
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