Kupke, Laura S. and Dropco, Ivor and Goetz, Markus and Kupke, Paul and Jung, Friedrich and Stroszczynski, Christian and Jung, Ernst-Michael (2024) Contrast-Enhanced Intraoperative Ultrasound Shows Excellent Performance in Improving Intraoperative Decision-Making. LIFE-BASEL, 14 (9): 1199. ISSN , 2075-1729
Full text not available from this repository. (Request a copy)Abstract
Background: The aim of this study was to evaluate the performance and the impact of contrast-enhanced intraoperative ultrasound (CE-IOUS) on intraoperative decision-making, as there is still no standardized protocol for its use. Therefore, we retrospectively analyzed multiple CE-IOUS performed in hepato-pancreatic-biliary surgery with respect to pre- and postoperative imaging and histopathological findings. Methods: Data of 50 patients who underwent hepato-pancreatic-biliary surgery between 03/2022 and 03/2024 were retrospectively collected. CE-IOUS was performed with a linear 6-9 MHz multifrequency probe connected to a high-resolution device. The ultrasound contrast agent used was a stabilized aqueous suspension of sulphur hexafluoride microbubbles. Results: In total, all 50 lesions indicated for surgery were correctly identified. In 30 cases, CE-IOUS was used to localize the primary lesion and to define the resection margins. In the remaining 20 cases, CE-IOUS identified an additional lesion. Fifteen of these findings were identified as malignant. In eight of these cases, the additional malignant lesion was subsequently resected. In the remaining seven cases, CE-IOUS again revealed an inoperable situation. In summary, CE-IOUS diagnostics resulted in a high correct classification rate of 95.7%, with positive and negative predictive values of 95.2% and 100.0%, respectively. Conclusions: CE-IOUS shows excellent performance in describing intraoperative findings in hepato-pancreatic-biliary surgery, leading to a substantial impact on intraoperative decision-making.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FOCAL LIVER-LESIONS; SURGERY; MICROVASCULARIZATION; IMPACT; CEUS; ultrasound; contrast-enhanced ultrasound; CEUS; micro-vascularization; intraoperative ultrasound; IOUS; intraoperative decision-making |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 24 Jul 2025 12:29 |
| Last Modified: | 24 Jul 2025 12:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/63689 |
Actions (login required)
 |
View Item |
